Food as medicine: targeting the uraemic phenotype in chronic kidney disease
D Mafra, NA Borges, B Lindholm, PG Shiels… - Nature Reviews …, 2021 - nature.com
The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …
[HTML][HTML] Telomere length and all-cause mortality: a meta-analysis
Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …
diseases. Reports of association between telomere length (TL) and all-cause mortality …
[HTML][HTML] Physical activity and telomere length: Impact of aging and potential mechanisms of action
Telomeres protect the integrity of information-carrying DNA by serving as caps on the
terminal portions of chromosomes. Telomere length decreases with aging, and this …
terminal portions of chromosomes. Telomere length decreases with aging, and this …
Chronic kidney disease and premature ageing
JP Kooman, P Kotanko, AMWJ Schols… - Nature Reviews …, 2014 - nature.com
Chronic kidney disease (CKD) shares many phenotypic similarities with other chronic
diseases, including heart failure, chronic obstructive pulmonary disease, HIV infection and …
diseases, including heart failure, chronic obstructive pulmonary disease, HIV infection and …
Understanding how we age: insights into inflammaging
Inflammaging is characterized by the upregulation of the inflammatory response that occurs
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …
Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study
There is increasing interest in discovering mechanisms that mediate the effects of childhood
stress on late-life disease morbidity and mortality. Previous studies have suggested one …
stress on late-life disease morbidity and mortality. Previous studies have suggested one …
Inflammation and premature aging in advanced chronic kidney disease
JP Kooman, MJ Dekker, LA Usvyat… - American Journal …, 2017 - journals.physiology.org
Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …
and a catalyst for other complications, which are related to a premature aging phenotype …
Gender and telomere length: systematic review and meta-analysis
Background It is widely believed that females have longer telomeres than males, although
results from studies have been contradictory. Methods We carried out a systematic review …
results from studies have been contradictory. Methods We carried out a systematic review …
Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999–2002
The purpose of this study was to examine the association between socioeconomic status
(SES) and leukocyte telomere length (LTL)–a marker of cell aging that has been linked to …
(SES) and leukocyte telomere length (LTL)–a marker of cell aging that has been linked to …
Discrimination, racial bias, and telomere length in African-American men
Background Leukocyte telomere length (LTL) is an indicator of general systemic aging, with
shorter LTL being associated with several chronic diseases of aging and earlier mortality …
shorter LTL being associated with several chronic diseases of aging and earlier mortality …