Food as medicine: targeting the uraemic phenotype in chronic kidney disease

D Mafra, NA Borges, B Lindholm, PG Shiels… - Nature Reviews …, 2021 - nature.com
The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

[HTML][HTML] Telomere length and all-cause mortality: a meta-analysis

Q Wang, Y Zhan, NL Pedersen, F Fang, S Hägg - Ageing research reviews, 2018 - Elsevier
Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …

[HTML][HTML] Physical activity and telomere length: Impact of aging and potential mechanisms of action

NC Arsenis, T You, EF Ogawa, GM Tinsley, L Zuo - Oncotarget, 2017 - ncbi.nlm.nih.gov
Telomeres protect the integrity of information-carrying DNA by serving as caps on the
terminal portions of chromosomes. Telomere length decreases with aging, and this …

Chronic kidney disease and premature ageing

JP Kooman, P Kotanko, AMWJ Schols… - Nature Reviews …, 2014 - nature.com
Chronic kidney disease (CKD) shares many phenotypic similarities with other chronic
diseases, including heart failure, chronic obstructive pulmonary disease, HIV infection and …

Understanding how we age: insights into inflammaging

D Baylis, DB Bartlett, HP Patel, HC Roberts - Longevity & healthspan, 2013 - Springer
Inflammaging is characterized by the upregulation of the inflammatory response that occurs
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …

Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study

I Shalev, TE Moffitt, K Sugden, B Williams… - Molecular …, 2013 - nature.com
There is increasing interest in discovering mechanisms that mediate the effects of childhood
stress on late-life disease morbidity and mortality. Previous studies have suggested one …

Inflammation and premature aging in advanced chronic kidney disease

JP Kooman, MJ Dekker, LA Usvyat… - American Journal …, 2017 - journals.physiology.org
Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …

Gender and telomere length: systematic review and meta-analysis

M Gardner, D Bann, L Wiley, R Cooper, R Hardy… - Experimental …, 2014 - Elsevier
Background It is widely believed that females have longer telomeres than males, although
results from studies have been contradictory. Methods We carried out a systematic review …

Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999–2002

BL Needham, N Adler, S Gregorich, D Rehkopf… - Social science & …, 2013 - Elsevier
The purpose of this study was to examine the association between socioeconomic status
(SES) and leukocyte telomere length (LTL)–a marker of cell aging that has been linked to …

Discrimination, racial bias, and telomere length in African-American men

DH Chae, AM Nuru-Jeter, NE Adler, GH Brody… - American journal of …, 2014 - Elsevier
Background Leukocyte telomere length (LTL) is an indicator of general systemic aging, with
shorter LTL being associated with several chronic diseases of aging and earlier mortality …