Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities

C Hu, J Yang, Z Qi, H Wu, B Wang, F Zou, H Mei… - MedComm, 2022 - Wiley Online Library
The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …

Comparative assessment of vascular function in autoimmune rheumatic diseases: considerations of prevention and treatment

P Soltész, G Kerekes, H Dér, G Szücs, S Szántó… - Autoimmunity …, 2011 - Elsevier
Numerous autoimmune-inflammatory rheumatic diseases have been associated with
accelerated atherosclerosis or other types of vasculopathy leading to increased cardio-and …

Anti-C1q antibodies in systemic lupus erythematosus

AM Orbai, L Truedsson, G Sturfelt, O Nived, H Fang… - Lupus, 2015 - journals.sagepub.com
Objective Anti-C1q has been associated with systemic lupus erythematosus (SLE) and lupus
nephritis in previous studies. We studied anti-C1q specificity for SLE (vs rheumatic disease …

Anti-C1q autoantibodies, novel tests, and clinical consequences

M Mahler, RA van Schaarenburg, LA Trouw - Frontiers in immunology, 2013 - frontiersin.org
Although anti-C1q autoantibodies have been described more than four decades ago a
constant stream of papers describing clinical associations or functional consequences …

Immunological aspects of heat-shock proteins—the optimum stress of life

Z Prohászka, G Füst - Molecular immunology, 2004 - Elsevier
This review summarizes the complex role of heat-shock proteins (Hsp) in immune reactions,
especially the cellular effects of heat-shock proteins during the recognition processes by …

The pathophysiological role of heat shock response in autoimmunity: a literature review

A Androvitsanea, K Stylianou, E Drosataki, I Petrakis - Cells, 2021 - mdpi.com
Within the last two decades, there has been increasing evidence that heat-shock proteins
can have a differential influence on the immune system. They can either provoke or …

[HTML][HTML] Antibodies against heat shock proteins in environmental stresses and diseases: friend or foe?

T Wu, RM Tanguay - Cell stress & chaperones, 2006 - ncbi.nlm.nih.gov
Heat shock proteins (Hsps) can be found in two forms, intracellular and extracellular. The
intracellular Hsps are induced as a result of stress and have been found to be cytoprotective …

C1q, antibodies and anti-C1q autoantibodies

FJ Beurskens, RA van Schaarenburg, LA Trouw - Molecular immunology, 2015 - Elsevier
The complement system has long been known for its role in combating infections. More
recently the complement system is becoming increasingly appreciated for its role in …

Atherosclerosis and macrovascular involvement in systemic sclerosis: myth or reality

U Nussinovitch, Y Shoenfeld - Autoimmunity Reviews, 2011 - Elsevier
Systemic sclerosis (SSc) is a chronic disease of unknown etiology, characterized by
enhanced fibrosis, and microvascular abnormalities. During the past several decades, the …

Complement component C1q and anti‐C1q antibodies in theory and in clinical practice

E Potlukova, P Kralikova - Scandinavian journal of immunology, 2008 - Wiley Online Library
The complement system is a major part of the innate immunity. The first component of the
classical pathway of complement activation, C1q, plays a crucial role in the clearance of …