Nanocapsules for drug delivery: an updated review of the last decade

N Erdoğar, S Akkın, E Bilensoy - Recent Patents on Drug …, 2018 - ingentaconnect.com
Background: For the past few decades, there has been considerable research interest in
drug delivery strategies using nanoparticulate systems as carriers for a wide range of active …

Drug targeting strategies into the brain for treating neurological diseases

W Barnabas - Journal of neuroscience methods, 2019 - Elsevier
Brain specific drug delivery is one of the most interesting and challenging areas of research.
The blood-brain barrier separates the brain from blood and acts as a barrier to protect the …

[HTML][HTML] A comparison study of lipid and polymeric nanoparticles in the nasal delivery of meloxicam: Formulation, characterization, and in vitro evaluation

H Akel, R Ismail, G Katona, F Sabir, R Ambrus… - International Journal of …, 2021 - Elsevier
With the increasingly widespread of central nervous system (CNS) disorders and the lack of
sufficiently effective medication, meloxicam (MEL) has been reported as a possible …

[图书][B] Encyclopedia of Polymer Applications, 3 Volume Set

M Mishra - 2018 - taylorfrancis.com
Undoubtedly the applications of polymers are rapidly evolving. Technology is continually
changing and quickly advancing as polymers are needed to solve a variety of day-to-day …

Therapeutic nanotechnologies for Alzheimer's disease: A critical analysis of recent trends and findings

P Delbreil, JM Rabanel, X Banquy… - Advanced Drug Delivery …, 2022 - Elsevier
Alzheimer's Disease (AD) is an irreversible neurodegenerative disease for which no
modifying therapies are presently available. Besides the identification of pathological …

A novel albumin wrapped nanosuspension of meloxicam to improve inflammation-targeting effects

Q Li, F Chen, Y Liu, S Yu, X Gai, M Ye… - International journal …, 2018 - Taylor & Francis
Background The objective of this study was to develop a more bio-available and safe
nanosuspension of meloxicam (MX), which could dramatically improve inflammation …

The emerging role of COX-2, 15-LOX and PPARγ in metabolic diseases and cancer: an introduction to novel multi-target directed ligands (MTDLs)

RA Alaaeddine, PA Elzahhar, I AlZaim… - Current Medicinal …, 2021 - ingentaconnect.com
Emerging evidence supports an intertwining framework for the involvement of different
inflammatory pathways in a common pathological background for a number of disorders. Of …

Nanobiotechnology in neurodegenerative diseases

J Jampílek, K Kráľová, P Novák, M Novák - Nanobiotechnology in …, 2019 - Springer
Abstract “Neurodegenerative disease” is a term for a variety of disorders that primarily affect
neurons in the human brain and spinal cord. These diseases are presently incurable and …

Meloxicam inhibits apoptosis in neurons by deactivating tumor necrosis factor receptor superfamily member 25, leading to the decreased cleavage of dna …

P Guan, D Zhu, P Wang - Molecular Neurobiology, 2023 - Springer
Neuronal apoptosis is considered to be a critical cause of Alzheimer's disease (AD).
Recently, meloxicam has shown neuroprotective effects; however, the inherent mechanisms …

Development of in situ gelling meloxicam-human serum albumin nanoparticle formulation for nose-to-brain application

G Katona, B Sipos, M Budai-Szűcs, GT Balogh… - Pharmaceutics, 2021 - mdpi.com
The aim of this study was to develop an intranasal in situ thermo-gelling meloxicam-human
serum albumin (MEL-HSA) nanoparticulate formulation applying poloxamer 407 (P407) …