Evaluation of the antiapoptotic and anti-inflammatory properties of chitosan in methotrexate-induced oral mucositis in rats
Background Methotrexate (MTX), a chemotherapeutic agent, is known to cause oral
mucositis. Chitosan has been shown to have a protective effect in inflammatory animal …
mucositis. Chitosan has been shown to have a protective effect in inflammatory animal …
Quillaja saponaria bark saponin attenuates methotrexate induced hepatic oxidative stress, inflammation and associated liver injury in rats
Quillaja saponaria Molina tree bark represents the main source of Q. saponaria saponin that
has antitussive-, antiinflammatory-, and immune-stimulant effects. In spite of such multiple …
has antitussive-, antiinflammatory-, and immune-stimulant effects. In spite of such multiple …
Cardio-protective impact of gabapentin against doxorubicin-induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling
Purpose Cardiotoxicity is one of the most commonly encountered adverse effects observed
alongside the therapeutic use of doxorubicin (DOX), thus curbing its therapeutic utility …
alongside the therapeutic use of doxorubicin (DOX), thus curbing its therapeutic utility …
Quillaja saponin mitigates methotrexate-provoked renal injury; insight into Nrf-2/Keap-1 pathway modulation with suppression of oxidative stress and inflammation
MA Abdel-Reheim, ME Ali, AGA Gaafar… - … of Pharmaceutical Health …, 2024 - Springer
Background Methotrexate (MTX) is an antineoplastic/immunosuppressive drug, whose
clinical use is impeded owing to its serious adverse effects; one of which is acute kidney …
clinical use is impeded owing to its serious adverse effects; one of which is acute kidney …
Tranilast abrogates cisplatin‐induced testicular and epididymal injuries: An insight into its modulatory impact on apoptosis/proliferation
Cisplatin is a chemotherapeutic agent whose therapeutic use is greatly limited by the
associated organs' toxicity and particularly, testicular toxicity. Cisplatin‐induced testicular …
associated organs' toxicity and particularly, testicular toxicity. Cisplatin‐induced testicular …
Ramelteon and mechanism of its restorative effect in an experimental lung disease model
Methotrexate (MTX) is an anticancer agent widely used in clinical practice for various
oncological, rheumatological, autoimmune, and inflammatory diseases. However, the side …
oncological, rheumatological, autoimmune, and inflammatory diseases. However, the side …
The key role of organic anion transporter 3 in the drug–drug interaction between tranilast and methotrexate
J Wang, W Yuan, Q Shen, Q Wu, Z Jiang… - … of Biochemical and …, 2022 - Wiley Online Library
Abstract Tranilast, N‐(3′, 4′‐dimethoxycinnamoyl)‐anthranilic acid, is an anti‐allergic
drug and is considered for use in the treatment of rheumatoid arthritis. Methotrexate, an …
drug and is considered for use in the treatment of rheumatoid arthritis. Methotrexate, an …
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
FB Karakaya-Cimen, C Macit, GG Sivas… - European Journal of …, 2023 - dergipark.org.tr
Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity
used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax …
used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax …
[PDF][PDF] Protective Effect of Linoleic Acid on Liver Toxicity Induced By Methotrexate.
AG Kabakcı, MG Bozkır - International Journal of Morphology, 2023 - intjmorphol.com
We aimed to investigate the protective effect of linoleic acid on liver toxicity induced by
methotrexate. The study was carried out in partnership with the Department of Anatomy and …
methotrexate. The study was carried out in partnership with the Department of Anatomy and …
Efecto Protector del Ácido Linoleico sobre la Toxicidad Hepática Inducida por Metotrexato
AG Kabakcı, MG Bozkır - International Journal of Morphology, 2023 - SciELO Chile
We aimed to investigate the protective effect of linoleic acid on liver toxicity induced by
methotrexate. The study was carried out in partnership with the Department of Anatomy and …
methotrexate. The study was carried out in partnership with the Department of Anatomy and …