[HTML][HTML] GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer's disease

J Jiménez-Balado, TS Eich - Seminars in cell & developmental biology, 2021 - Elsevier
In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …

Amyloid-β: a potential link between epilepsy and cognitive decline

M Romoli, A Sen, L Parnetti, P Calabresi… - Nature Reviews …, 2021 - nature.com
People with epilepsy—in particular, late-onset epilepsy of unknown aetiology—have an
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …

Post-stroke everything

A Lekoubou, C Nguyen, M Kwon, AD Nyalundja… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims at providing updates on selected post-stroke
complications. We examined recent advances in diagnosing and treating the following post …

Clinical, imaging, and biomarker evidence of amyloid-and tau-related neurodegeneration in late-onset epilepsy of unknown etiology

LB Hickman, JM Stern, DHS Silverman… - Frontiers in …, 2023 - frontiersin.org
Accumulating evidence suggests amyloid and tau-related neurodegeneration may play a
role in development of late-onset epilepsy of unknown etiology (LOEU). In this article, we …

[HTML][HTML] Late-onset epilepsy clinic: from clinical diagnostics to biomarkers

V Punia, S Bhansali, C Tsai - Seizure: European Journal of Epilepsy, 2024 - Elsevier
The unique patho-clinical entity of late-onset epilepsy (LOE), distinguished by its distinct
natural history, from its onset to the prognosis it portends, necessitates specialized care. We …

Mortality in patients with late-onset epilepsy: results from the atherosclerosis risk in communities study

EL Johnson, GL Krauss, A Kucharska-Newton… - Neurology, 2021 - AAN Enterprises
Background and Objectives To determine the risk of mortality and causes of death in
persons with late-onset epilepsy (LOE) compared to those without epilepsy in a community …

Epilepsy, vascular risk factors, and cognitive decline in older adults: the cardiovascular health study

H Choi, MSV Elkind, WT Longstreth Jr, AK Boehme… - Neurology, 2022 - AAN Enterprises
Background and Objectives Recent studies have shown that global cognitive ability tends to
decline faster over time in older adults (≥ 65 years) with epilepsy compared with older …

Late‐onset epilepsy and 25‐year cognitive change: The Atherosclerosis Risk in Communities (ARIC) study

EL Johnson, GL Krauss, KA Walker, J Brandt… - …, 2020 - Wiley Online Library
Objective To define the association between late‐onset epilepsy (LOE) and 25‐year change
in cognitive performance. Methods The Atherosclerosis Risk in Communities (ARIC) study is …

Structural brain network deviations predict recovery after traumatic brain injury

JJ Gugger, N Sinha, Y Huang, AE Walter, C Lynch… - NeuroImage: Clinical, 2023 - Elsevier
Objective Traumatic brain injury results in diffuse axonal injury and the ensuing maladaptive
alterations in network function are associated with incomplete recovery and persistent …

Late-onset epilepsy predicts stroke: systematic review and meta-analysis

J Wall, J Knight, HCA Emsley - Epilepsy & Behavior, 2021 - Elsevier
Objective Late-onset epilepsy (LOE) is closely associated with cerebrovascular disease,
acting as both a marker of cerebrovascular disease (CVD) and occurring as a direct …