Cartilage-inspired hydrogel with mechanical adaptability, controllable lubrication, and inflammation regulation abilities

P Yu, Y Li, H Sun, X Ke, J Xing, Y Zhao… - … Applied Materials & …, 2022 - ACS Publications
Cartilage is a key component in joints because of its load-bearing and lubricating abilities.
However, osteoarthritis often leads to afunction of load-bearing/lubrication and occurrence …

[HTML][HTML] Advances in nanoenabled 3D matrices for cartilage repair

CL Pereira, M Lamghari, B Sarmento - Acta Biomaterialia, 2022 - Elsevier
Cartilage repair strategies are evolving at a fast pace with technology development. Matrices
that offer multifaceted functions and a full adaption to the cartilage defect are of pivotal …

Recent Strategies and Advances in Hydrogel-Based Delivery Platforms for Bone Regeneration

X Wang, J Zeng, D Gan, K Ling, M He, J Li, Y Lu - Nano-Micro Letters, 2025 - Springer
Bioactive molecules have shown great promise for effectively regulating various bone
formation processes, rendering them attractive therapeutics for bone regeneration. However …

Chemonucleolysis combined with dynamic loading for inducing degeneration in bovine caudal intervertebral discs

A Vernengo, H Bumann, N Kluser… - … in Bioengineering and …, 2023 - frontiersin.org
Chemonucleolysis has become an established method of producing whole organ culture
models of intervertebral disc (IVD) degeneration. However, the field needs more side-by …

Bioinspired bottlebrush polymers effectively alleviate frictional damage both in vitro and in vivo

DA Pham, CS Wang, L Séguy, H Zhang… - Advanced …, 2024 - Wiley Online Library
Bottlebrush polymers (BB) have emerged as compelling candidates for biosystems to face
tribological challenges, including friction and wear. This study provides a comprehensive …

Digital light processing bioprinted human chondrocyte-laden poly (γ-glutamic acid)/hyaluronic acid bio-ink towards cartilage tissue engineering

AKX Lee, YH Lin, CH Tsai, WT Chang, TL Lin, MY Shie - Biomedicines, 2021 - mdpi.com
Cartilage injury is the main cause of disability in the United States, and it has been projected
that cartilage injury caused by osteoarthritis will affect 30% of the entire United States …

Electrospun fibrous membrane reinforced hydrogels with preferable mechanical and tribological performance as cartilage substitutes

Q Chen, X Yan, K Chen, C Feng, D Wang… - Journal of Materials …, 2023 - pubs.rsc.org
Hydrogels have attracted much attention as cartilage substitutes due to their human tissue-
like characteristics. However, developing cartilage substitutes require the combination of …

Engineered high-strength biohydrogel as a multifunctional platform to deliver nucleic acid for ameliorating intervertebral disc degeneration

T Chen, Q Qian, P Makvandi, EN Zare, Q Chen… - Bioactive Materials, 2023 - Elsevier
Intervertebral disc degeneration (IVDD) is a leading cause of low back pain. The strategy of
using functional materials to deliver nucleic acids provides a powerful tool for ameliorating …

Cartilage tissue healing and regeneration based on biocompatible materials: a systematic review and bibliometric analysis from 1993 to 2022

MX Yao, YF Zhang, W Liu, HC Wang, C Ren… - Frontiers in …, 2024 - frontiersin.org
Cartilage, a type of connective tissue, plays a crucial role in supporting and cushioning the
body, and damages or diseases affecting cartilage may result in pain and impaired joint …

[PDF][PDF] Mimicking Intervertebral Disc Mechanical Properties with Functionally Graded Auxetic Composites

PL DE ALMEIDA - 2021 - run.unl.pt
Disc degeneration is a health issue which affects the worldwide population. Even though
spinal fusion presents a good solution to this issue, in the long term it displays several …