Stroke is the world's leading cause of disability with limited brain repair treatments which
effectively improve long‐term neurological deficits. The neuroinflammatory responses …

Ischemic stroke is one of the major causes of global disability and death. Comorbidities in
stroke are not only risk factors for an increased incidence of stroke, but also adversely …

Background and Purpose—Type 2 diabetes mellitus (T2DM) is a major comorbidity that
exacerbates ischemic brain injury and worsens functional outcome after stroke. T2DM is …

Stroke therapy has entered a new era highlighted by the use of endovascular therapy in
addition to intravenous thrombolysis. However, the efficacy of current therapeutic regimens …

Introduction The neuroprotective effects of hypothermia in acute ischemic stroke are well
documented. However, the mechanisms involved in the effects remain to be clearly …

Aims. Stroke is a leading cause of morbidity and mortality. This study aimed to determine
whether nicotinamide administration could improve remyelination after stroke and reveal the …

Patients with type 2 diabetes mellitus (T2DM) exhibit a distinct and high risk of ischemic
stroke with worse post-stroke neurovascular and white matter (WM) prognosis than the non …

Cerebral ischemia in diabetics results in severe brain damage. Different animal models of
cerebral ischemia have been used to study the aggravation of ischemic brain damage in the …

Background Altered neural activity based on the fractional amplitude of low-frequency
fluctuations (fALFF) has been reported in patients with diabetes. However, whether fALFF …

Background Ischemic stroke often induces profound white matter lesions, resulting in poor
neurological outcomes and impaired post-stroke recovery. The present study aimed to …