[HTML][HTML] 5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

C Sethy, CN Kundu - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Fluorouracil (5-FU) has been an important anti-cancer drug to date. With an increase in the
knowledge of its mechanism of action, various treatment modalities have been developed …

Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies

L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

The roles of autophagy in cancer

CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

Cancer stem cells (CSCs) in cancer progression and therapy

M Najafi, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …

The current knowledge concerning solid cancer and therapy

M Najafi, J Majidpoor, H Toolee… - Journal of biochemical …, 2021 - Wiley Online Library
Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Melatonin and 5-fluorouracil combination chemotherapy: opportunities and efficacy in cancer therapy

A Mafi, M Rezaee, N Hedayati, SD Hogan… - Cell Communication and …, 2023 - Springer
Combined chemotherapy is a treatment method based on the simultaneous use of two or
more therapeutic agents; it is frequently necessary to produce a more effective treatment for …

Melatonin and its ubiquitous anticancer effects

S Bhattacharya, KK Patel, D Dehari, AK Agrawal… - Molecular and cellular …, 2019 - Springer
Abstract Melatonin (N-acetyl-5-methoxy-tryptamine), which is generally considered as
pleiotropic and multitasking molecule, secretes from pineal gland at night under normal light …

Role and therapeutic potential of melatonin in various type of cancers

S Gurunathan, M Qasim, MH Kang… - OncoTargets and …, 2021 - Taylor & Francis
Cancer is a large group of diseases and the second leading cause of death worldwide.
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …

Association between night-shift work and cancer risk: updated systematic review and meta-analysis

A Dun, X Zhao, X Jin, T Wei, X Gao, Y Wang… - Frontiers in …, 2020 - frontiersin.org
Background: Nightshift work introduces light at night and causes circadian rhythm among
night workers, who are considered to be at increased risk of cancer. However, in the last 2 …

ALDH1: A potential therapeutic target for cancer stem cells in solid tumors

Y Wei, Y Li, Y Chen, P Liu, S Huang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Solid tumors can be divided into benign solid tumors and solid malignant tumors in the
academic community, among which malignant solid tumors are called cancers. Cancer is …