[HTML][HTML] Stem cell-based therapy for human diseases
DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …
Cardiomyocyte maturation: new phase in development
Y Guo, WT Pu - Circulation research, 2020 - Am Heart Assoc
Maturation is the last phase of heart development that prepares the organ for strong,
efficient, and persistent pumping throughout the mammal's lifespan. This process is …
efficient, and persistent pumping throughout the mammal's lifespan. This process is …
Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …
now can generate most cells of the human body in the laboratory. PSC-derived …
[PDF][PDF] Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
Bispecific antibodies: a mechanistic review of the pipeline
AF Labrijn, ML Janmaat, JM Reichert… - Nature reviews Drug …, 2019 - nature.com
The term bispecific antibody (bsAb) is used to describe a large family of molecules designed
to recognize two different epitopes or antigens. BsAbs come in many formats, ranging from …
to recognize two different epitopes or antigens. BsAbs come in many formats, ranging from …
Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates
YW Liu, B Chen, X Yang, JA Fugate, FA Kalucki… - Nature …, 2018 - nature.com
Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts
of infarcted myocardium and beat in synchrony with the heart, but in some settings cause …
of infarcted myocardium and beat in synchrony with the heart, but in some settings cause …
[HTML][HTML] Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
S Funakoshi, I Fernandes, O Mastikhina… - Nature …, 2021 - nature.com
Compact cardiomyocytes that make up the ventricular wall of the adult heart represent an
important therapeutic target population for modeling and treating cardiovascular diseases …
important therapeutic target population for modeling and treating cardiovascular diseases …
Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
Y Shiba, T Gomibuchi, T Seto, Y Wada, H Ichimura… - Nature, 2016 - nature.com
Induced pluripotent stem cells (iPSCs) constitute a potential source of autologous patient-
specific cardiomyocytes for cardiac repair, providing a major benefit over other sources of …
specific cardiomyocytes for cardiac repair, providing a major benefit over other sources of …
High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
Cardiomyocyte regeneration: a consensus statement
Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …