Osteoarthritis (OA) is a disease of the whole joint organ, characterized by the loss of
cartilage, and structural changes in bone including the formation of osteophytes, causing …

Cartilage oligomeric matrix protein (COMP) is an extracellular matrix (ECM) glycoprotein that
is critical for collagen assembly and ECM stability. Mutations of COMP cause endoplasmic …

Serum biomarkers of osteoarticular diseases have been in the limelight of current clinical
research trends. Laboratory validation of defined and candidate biomarkers for both …

In recent years, markers research has focused on the structural components of cartilage
matrix. Specifically, a second generation of degradation markers has been developed …

Background: The aim of this study is to determine the effect of three doses of intra-articular
injection of platelet-rich plasma (PRP) into the osteoarthritic (OA) knee joint on the functional …

Background Knee osteoarthritis (OA) is one of the most common structural OA disorders
globally. Incomplete understanding of the fundamental biological aspects of osteoarthritis …

Osteoarthritis, a highly age-related and chronic inflammatory disorder with cartilage loss,
causes patients difficultly in movement; there is no efficient and sustainable remedy for …

In general populations, age-dependent renal impairment contributes to the progression of
renal dysfunction. It has not been known which molecules are involved in age-dependent …

Posttraumatic osteoarthritis (PTOA) is a special form of OA, developing after joint injuries.
Except for some minor differences between the clinical characteristics of patients suffering …

Acute kidney injury (AKI) is a type of renal disease occurs frequently in hospitalized patients,
which may cause abnormal renal function and structure with increase in serum creatinine …