Major review: exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology

IF Aboobakar, WM Johnson, WD Stamer… - Experimental eye …, 2017 - Elsevier
Exfoliation syndrome (XFS) is a common age-related disorder that leads to deposition of
extracellular fibrillar material throughout the body. The most recognized disease …

The interactions of genes, age, and environment in glaucoma pathogenesis

LP Doucette, A Rasnitsyn, M Seifi, MA Walter - Survey of ophthalmology, 2015 - Elsevier
Glaucoma, a progressive degenerative condition that results in the death of retinal ganglion
cells, is one of the leading causes of blindness, affecting millions worldwide. The …

Primary open-angle glaucoma preferred practice pattern®

SJ Gedde, K Vinod, MM Wright, KW Muir, JT Lind… - Ophthalmology, 2021 - Elsevier
Background Primary open angle glaucoma (POAG) is a chronic, progressive ocular disease
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …

Ocular and systemic manifestations of exfoliation syndrome

R Ritch - Journal of glaucoma, 2014 - journals.lww.com
Exfoliation syndrome is an age-related disease characterized by the production and
progressive accumulation of a fibrillar extracellular material in many ocular tissues. It leads …

Genetics of pseudoexfoliation syndrome

P Challa - Current opinion in ophthalmology, 2009 - journals.lww.com
Genetics of pseudoexfoliation syndrome : Current Opinion in Ophthalmology Genetics of
pseudoexfoliation syndrome : Current Opinion in Ophthalmology Log in or Register Subscribe …

Association of gene polymorphisms with primary open angle glaucoma: a systematic review and meta-analysis

M Chen, X Yu, J Xu, J Ma, X Chen… - … & visual science, 2019 - iovs.arvojournals.org
Methods: We searched in PubMed and Web of Science (up to January 10, 2018) for genetic
studies of POAG. All case control studies investigating the association between single …

[HTML][HTML] Ethnicity-based subgroup meta-analysis of the association of LOXL1 polymorphisms with glaucoma

H Chen, LJ Chen, M Zhang, W Gong, POS Tam… - Molecular …, 2010 - ncbi.nlm.nih.gov
Purpose To investigate the association and ethnic heterogeneity of lysyl oxidase-like 1
(LOXL1) single nucleotide polymorphisms (SNPs) with exfoliation syndrome …

Complex genetic mechanisms in glaucoma: an overview

KN Rao, S Nagireddy… - Indian journal of …, 2011 - journals.lww.com
Glaucomas comprise a group of hereditary optic neuropathies characterized by progressive
and irreversible visual field loss and damage to the optic nerve head. It is a complex disease …

Association of LOXL1 gene with Finnish exfoliation syndrome patients

S Lemmelä, E Forsman, P Onkamo, H Nurmi… - Journal of human …, 2009 - nature.com
In this study, three single-nucleotide polymorphisms (SNPs) on the lysyl oxidase-like 1
(LOXL1) gene associated with exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) …

[HTML][HTML] Association of LOXL1 polymorphisms with pseudoexfoliation in the Chinese

KYC Lee, SL Ho, A Thalamuthu, A Venkatraman… - Molecular …, 2009 - ncbi.nlm.nih.gov
Purpose Single nucleotide polymorphisms (SNPs) within the lysyl oxidase like-1 gene
(LOXL1; rs1048661 and rs3825942) were found to confer risk to pseudoexfoliation …