Most of the genes in the major histocompatibility complex (MHC) region express high
polymorphism that is fundamental for their function. The most important function of human …

Around 1–5% of all couples experience recurrent pregnancy loss (RPL). Established risk
factors include anatomical, genetic, endocrine, and hemostatic alterations. With around 50 …

STUDY QUESTION What is the recommended management of women with recurrent
pregnancy loss (RPL) based on the best available evidence in the literature? SUMMARY …

Immunohistochemistry was used to investigate the leukocyte populations in the
endometrium of women suffering recurrent miscarriage. Mid-luteal phase endometrial …

OBJECTIVE: To give an overview of currently used investigations and treatments offered to
women with recurrent pregnancy loss (RPL) and, from an evidence-based point of view, to …

Recurrent miscarriage (RM) occurs in 1–3% of couples aiming at childbirth. Due to
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …

Human reproductive failure may be a consequence of aberrant expression of immunological
factors during pregnancy. Although the relative importance of immunological factors in …

The etiology of a fraction of recurrent spontaneous abortions (RSA) may involve
immunological mechanisms. Aberrant profiles of Th1 and Th2 cytokines have been …

The role that maternal and fetal human leukocyte antigen (HLA) genes play in pregnancy is
unknown, but it has been suggested that fetuses whose HLA alleles do not differ from …

There are still controversies concerning the role of immunological mechanisms engaged
both in recurrent abortions (RA) and pre-eclampsia (PE). According to some opinions …