Spirooxindole: a versatile biologically active heterocyclic scaffold
Spirooxindoles occupy an important place in heterocyclic chemistry. Many natural
spirooxindole-containing compounds have been identified as bio-promising agents …
spirooxindole-containing compounds have been identified as bio-promising agents …
[HTML][HTML] Design, synthesis and molecular modeling of isatin-aminobenzoic acid hybrids as antibacterial and antibiofilm agents
AA Radwan, FK Al-Anazi, M Al-Agamy… - Saudi Pharmaceutical …, 2023 - Elsevier
Abstract Number of factors, including newly emerging infectious diseases and an increase in
multi-drug resistant microbial pathogens with particular relevance for Gram-positive bacteria …
multi-drug resistant microbial pathogens with particular relevance for Gram-positive bacteria …
C3-spirooxindoles: Divergent chemical synthesis and bioactivities (2018–2023)
This scientific review documents the recent progress of C 3-spirooxindoles chemistry
(synthesis and reaction mechanism) and their bioactivities, focusing on the promising results …
(synthesis and reaction mechanism) and their bioactivities, focusing on the promising results …
Chemometrically assisted evaluation of isatine derivatives' chromatographic and computational descriptors
S Apostolov, D Brkić, G Vastag - Journal of Liquid Chromatography …, 2023 - Taylor & Francis
The first phase of the evaluation of the biological profile of novel isatin derivatives included
the theoretical verification of their drug-likeness and lead-likeness properties. In the second …
the theoretical verification of their drug-likeness and lead-likeness properties. In the second …
Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective
The importance of indole‐based heterocycle scaffolds in medicinal chemistry has increased
as a result of their significant pharmacological and biological characteristics. These …
as a result of their significant pharmacological and biological characteristics. These …