Understanding cytokinesis: lessons from fission yeast

TD Pollard, JQ Wu - Nature reviews Molecular cell biology, 2010 - nature.com
For decades after the discovery that a contractile ring made of actin filaments and myosin II
produces the force to constrict the cleavage furrow of animal cells, the complexity of …

Rho GTPases: regulation of cell polarity and growth in yeasts

P Perez, SA Rincón - Biochemical Journal, 2010 - portlandpress.com
Eukaryotic cells display a wide range of morphologies important for cellular function and
development. A particular cell shape is made via the generation of asymmetry in the …

Assembly and architecture of precursor nodes during fission yeast cytokinesis

D Laporte, VC Coffman, IJ Lee, JQ Wu - Journal of Cell Biology, 2011 - rupress.org
The contractile ring is essential for cytokinesis in most fungal and animal cells. In fission
yeast, cytokinesis nodes are precursors of the contractile ring and mark the future cleavage …

Pombe's thirteen–control of fission yeast cell division by the septation initiation network

V Simanis - Journal of cell science, 2015 - journals.biologists.com
The septation initiation network (SIN) regulates aspects of cell growth and division in
Schizosaccharomyces pombe and is essential for cytokinesis. Insufficient signalling results …

Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site

RH Roberts-Galbraith, MD Ohi, BA Ballif, JS Chen… - Molecular cell, 2010 - cell.com
Cytokinesis in Schizosaccharomyces pombe requires the function of Cdc15, the founding
member of the pombe cdc15 homology (PCH) family of proteins. As an early, abundant …

α-Actinin and fimbrin cooperate with myosin II to organize actomyosin bundles during contractile-ring assembly

D Laporte, N Ojkic, D Vavylonis… - Molecular biology of the …, 2012 - Am Soc Cell Biol
The actomyosin contractile ring assembles through the condensation of a broad band of
nodes that forms at the cell equator in fission yeast cytokinesis. The condensation process …

Roles of formin nodes and myosin motor activity in Mid1p-dependent contractile-ring assembly during fission yeast cytokinesis

VC Coffman, AH Nile, IJ Lee, H Liu… - Molecular biology of the …, 2009 - Am Soc Cell Biol
Two prevailing models have emerged to explain the mechanism of contractile-ring assembly
during cytokinesis in the fission yeast Schizosaccharomyces pombe: the spot/leading cable …

Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast

F Meitinger, B Petrova, IM Lombardi… - Journal of cell …, 2010 - journals.biologists.com
The mitotic-exit network (MEN) is a signaling pathway that is essential for the coordination of
mitotic exit and cytokinesis. Whereas the role of the MEN in mitotic exit is well established …

Contractile‐ring assembly in fission yeast cytokinesis: Recent advances and new perspectives

IJ Lee, VC Coffman, JQ Wu - Cytoskeleton, 2012 - Wiley Online Library
The fission yeast Schizosaccharomyces pombe is an excellent model organism to study
cytokinesis. Here, we review recent advances on contractile‐ring assembly in fission yeast …

Hippo signalling in the G2/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways

A Hergovich, BA Hemmings - Seminars in cell & developmental biology, 2012 - Elsevier
Over the past decade Hippo kinase signalling has been established as an essential tumour
suppressor pathway controlling tissue growth in flies and mammals. All members of the …