[PDF][PDF] Gadolinium (III) chelates as MRI contrast agents: structure, dynamics, and applications

P Caravan, JJ Ellison, TJ McMurry… - Chemical …, 1999 - s.mriquestions.com
Gadolinium, an obscure lanthanide element buried in the middle of the periodic table, has in
the course of a decade become commonplace in medical diagnostics. Like platinum in …

Lanthanide-containing molecular and supramolecular polymetallic functional assemblies

JCG Bünzli, C Piguet - Chemical Reviews, 2002 - ACS Publications
As a result of the different degrees of stabilization experienced by the 4f, 5d, and 6s orbitals
occurring upon ionization of the neutral metal, the lanthanides (La-Lu, Z) 57-71) exist almost …

Inorganic and bioinorganic solvent exchange mechanisms

L Helm, AE Merbach - Chemical reviews, 2005 - ACS Publications
The simplest reaction on a metal ion in aqueous or nonaqueous solution is the exchange of
a solvent molecule between the first and second coordination shells (eq 1). This reaction is …

The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates

P Caravan, NJ Cloutier, MT Greenfield… - Journal of the …, 2002 - ACS Publications
MS-325 is a novel blood pool contrast agent for magnetic resonance imaging currently
undergoing clinical trials to assess blockage in arteries. MS-325 functions by binding to …

Mono-and polymetallic lanthanide-containing functional assemblies: a field between tradition and novelty

C Piguet, JCG Bünzli - Chemical Society Reviews, 1999 - pubs.rsc.org
The variable and versatile co-ordination behaviour of lanthanide metal ions, LnIII, limits their
selective introduction into organised molecular or supramolecular architectures. The design …

Relaxivity of MRI contrast agents

É Tóth, L Helm, AE Merbach - Contrast agents I: magnetic resonance …, 2002 - Springer
In the recent years Magnetic Resonance Imaging has evolved into one of the most powerful
diagnostic techniques in medicine, in part thanks to the application of suitable contrast …

Gadolinium loaded nanoparticles in theranostic magnetic resonance imaging

Y Liu, N Zhang - Biomaterials, 2012 - Elsevier
Theranostic magnetic resonance imaging (MRI) is now receiving a growing interest in
imaging-guided drug delivery, monitoring the treatment and personalized administration etc …

Gadolinium nanoparticles as diagnostic and therapeutic agents: Their delivery systems in magnetic resonance imaging and neutron capture therapy

A Narmani, B Farhood, H Haghi-Aminjan… - Journal of Drug Delivery …, 2018 - Elsevier
Gadolinium (Gd) chelates have been widely used as contrast agent in magnetic resonance
imaging (MRI). In addition to using MRI, they are interesting, as a radiosensitizer, in neutron …

The impact of rigidity and water exchange on the relaxivity of a dendritic MRI contrast agent

GM Nicolle, É Tóth, H Schmitt‐Willich… - … A European Journal, 2002 - Wiley Online Library
Variable‐temperature, multiple magnetic field 17O NMR, EPR and variable‐temperature 1H
nuclear magnetic relaxation dispersion (NMRD) measurement techniques have been …

Metal complexes of maltol and close analogues in medicinal inorganic chemistry

KH Thompson, CA Barta, C Orvig - Chemical Society Reviews, 2006 - pubs.rsc.org
The family of hydroxypyrones and close congeners, the hydroxypyridinones, is a particularly
versatile class of ligands. The most widely investigated for medicinal applications are the 3 …