Serine/arginine-rich splicing factor 2 (SRSF2) is an RNA-binding protein that plays important
roles in splicing of mRNA precursors. SRSF2 mutations are frequently found in patients with …

As a type of regulated cell death (RCD) mode, pyroptosis plays an important role in several
kinds of cancers. Pyroptosis is induced by different stimuli, whose pathways are divided into …

CRISPR/Cas9 technology enables the rapid generation of loss‐of‐function mutations in a
targeted gene in mammalian cells. A single cell harboring those mutations can be used to …

Lung cancer is the fastest growth rate of morbidity and mortality in nearly a decade, and
remains difficult to treat. Furthermore, the molecular mechanisms underlying its development …

Purpose: While effective targeted therapies exist for estrogen receptor–positive and HER2-
positive breast cancer, no such effective therapies exist for triple-negative breast cancer …

Background Crossbreeding is an important way to improve production beef cattle
performance. Pinan cattle is a new hybrid cattle obtained from crossing Piedmontese bulls …

Introduction Experimental and virtual screening contributes to the discovery of more than
50% of clinical candidates. Considering the similar concept and goals, early-phase drug …

Hepatocellular carcinoma (HCC) is one of the most common malignancies, which causes
serious financial burden worldwide. This study aims to investigate the potential mechanisms …

The cell cycle genes homology region (CHR) has been identified as a DNA element with an
important role in transcriptional regulation of late cell cycle genes. It has been shown that …

Abstract Objective Incidence of both Type 2 diabetes mellitus (T2DM) and hepatocellular
carcinoma (HCC) are rapidly increasing worldwide. One of the leading causes of HCC is …