Purpose The FLAME trial provides strong evidence that MR-guided external beam radiation
therapy (EBRT) focal boost for localized prostate cancer increases biochemical disease-free …

The fusion of cutting-edge imaging technologies with radiation therapy (RT) has catalyzed
transformative breakthroughs in cancer treatment in recent decades. It is critical for us to …

Background To evaluate the treatment outcomes and toxicity of definitive radiotherapy (RT)
for prostate cancer (PC) patients using the simultaneous integrated boost (SIB) technique …

Background In a recent phase III randomized control trial, delivering a focal radiotherapy
(RT) boost to tumors visible on MRI was shown to improve disease-free survival and …

The aim of this retrospective study was to identify clinical predictors of early biochemical
recurrence (BCR) in patients with high-risk prostate cancer (PCa) treated with carbon-ion …

Ever since its introduction as a diagnostic imaging tool the potential of magnetic resonance
imaging (MRI) in radiation therapy (RT) treatment simulation and planning has been …

Purpose To compare the biochemical failure (FFBF) and prostate cancer specific survival
(PCSS) rates of patients with intermediate‐risk prostate cancer (IR‐PC) who were treated …

Purpose To develop a machine learning (ML) model based on radiomic features (RF)
extracted from whole prostate gland magnetic resonance imaging (MRI) for prediction of …

There are numerous radiation modalities for the definitive treatment of localized prostate
cancer. Classic clinical trials have established the basic tenets of treatment approaches, and …

This thesis explored the impact of radiotherapy modality and dose escalation for high-risk
prostate cancer patient treatments. This research highlights the potential of combining …