Metabolic engineering has allowed the production of a diverse number of valuable
chemicals using microbial organisms. Many biological challenges for improving bio …

Metabolic engineering has the potential to produce from simple, readily available,
inexpensive starting materials a large number of chemicals that are currently derived from …

Global energy demand and environmental concerns have stimulated increasing efforts to
produce carbon-neutral fuels directly from renewable resources. Microbially derived …

The ability to adapt to stimuli is a defining feature of many biological systems and critical to
maintaining homeostasis. While it is well appreciated that negative feedback can be used to …

Heterologous pathways used in metabolic engineering may produce intermediates toxic to
the cell. Dynamic control of pathway enzymes could prevent the accumulation of these …

The past several years have witnessed an increased presence of control theoretic concepts
in synthetic biology. This review presents an organized summary of how these control …

Many compounds being considered as candidates for advanced biofuels are toxic to
microorganisms. This introduces an undesirable trade‐off when engineering metabolic …

As the search for alternatives to fossil fuels continues, microalgae have emerged as a
promising renewable feedstock for biodiesel. Many species contain high lipid concentrations …

During microbial production of solvent-like compounds, such as advanced biofuels and bulk
chemicals, accumulation of the final product can negatively impact the cultivation of the host …

Metabolite biosensors are central to current efforts toward precision engineering of
metabolism. Although most research has focused on building new biosensors, their …