Effective and safe proton pump inhibitor therapy in acid-related diseases–a position paper addressing benefits and potential harms of acid suppression

C Scarpignato, L Gatta, A Zullo, C Blandizzi… - BMC medicine, 2016 - Springer
Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

Helicobacter pylori treatment in the era of increasing antibiotic resistance

DY Graham, L Fischbach - Gut, 2010 - gut.bmj.com
With few exceptions, the most commonly recommended triple Helicobacter pylori regimen
(proton pump inhibitor (PPI), amoxicillin and clarithromycin) now provides unacceptably low …

Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption

F Megraud, S Coenen, A Versporten, M Kist… - Gut, 2013 - gut.bmj.com
Objective Resistance to antibiotics is the major cause of treatment failure of Helicobacter
pylori infection. A study was conducted to assess prospectively the antibacterial resistance …

Helicobacter pylori Infection

S Suerbaum, P Michetti - New England Journal of Medicine, 2002 - Mass Medical Soc
H. pylori is one of the most common bacterial infections in human beings, and its discovery
20 years ago altered the diagnosis and treatment of gastroduodenal disease. This review …

Peptic ulcer disease

P Malfertheiner, FKL Chan, KEL McColl - The lancet, 2009 - thelancet.com
Peptic ulcer disease had a tremendous effect on morbidity and mortality until the last
decades of the 20th century, when epidemiological trends started to point to an impressive …

H pylori antibiotic resistance: prevalence, importance, and advances in testing

F Megraud - Gut, 2004 - gut.bmj.com
Triple therapy, including two antibiotics, amoxicillin and clarithromycin, and a proton pump
inhibitor given for a week has been recommended as the treatment of choice at several …

Current concepts in the management of Helicobacter pylori infection—The Maastricht 2‐2000 Consensus Report

P Malfertheiner, F Megraud, C O'morain… - Alimentary …, 2002 - Wiley Online Library
Significant progress and new insights have been gained in the 4 years since the first
Maastricht Consensus Report, necessitating an update of the original guidelines. To achieve …

Novel and Effective Therapeutic Regimens for Helicobacter pylori in an Era of Increasing Antibiotic Resistance

Y Hu, Y Zhu, NH Lu - Frontiers in cellular and infection microbiology, 2017 - frontiersin.org
Helicobacter pylori (H. pylori) is a common gastrointestinal bacterial strain closely
associated with the incidence of chronic gastritis, peptic ulcers, gastric mucosa-associated …

Guidelines for the Management of Helicobacter pylori Infection in Japan: 2009 Revised Edition

M Asaka, M Kato, S Takahashi, Y Fukuda… - …, 2010 - Wiley Online Library
Background: Over the past few years, the profile of Helicobacter pylori infection has changed
in Japan. In particular, the relationship between H. pylori and gastric cancer has been …

Meta‐analysis: the effect of antibiotic resistance status on the efficacy of triple and quadruple first‐line therapies for Helicobacter pylori

L Fischbach, EL Evans - Alimentary pharmacology & …, 2007 - Wiley Online Library
Background Information regarding the effects of drug resistance on therapies for
Helicobacter pylori is limited. Aims To determine the effect of drug resistance on the efficacy …