Genetic susceptibility to autoimmune thyroid disease: past, present, and future

Y Tomer - Thyroid, 2010 - liebertpub.com
Background: Autoimmune thyroid diseases (AITD), including Graves' disease and
Hashimoto's thyroiditis, arise due to complex interactions between environmental and …

Autoimmune thyroid disease

N Stathatos, GH Daniels - Current opinion in rheumatology, 2012 - journals.lww.com
Autoimmune thyroid disease : Current Opinion in Rheumatology Autoimmune thyroid disease :
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get new …

The etiology of autoimmune thyroid disease: a story of genes and environment

Y Tomer, A Huber - Journal of autoimmunity, 2009 - Elsevier
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's
thyroiditis (HT) are prevalent autoimmune diseases, affecting up to 5% of the general …

Autoimmune thyroiditis and diabetes: dissecting the joint genetic susceptibility in a large cohort of multiplex families

MJB Villano, AK Huber, DA Greenberg… - The Journal of …, 2009 - academic.oup.com
Context: Epidemiological data support a shared genetic susceptibility to autoimmune thyroid
disease (AITD) and type 1 diabetes (T1D). Both diseases frequently occur within the same …

[HTML][HTML] Thyroid disease and autoimmune diseases

JS Franco, J Amaya-Amaya… - Autoimmunity: From Bench …, 2013 - ncbi.nlm.nih.gov
Autoimmune thyroid diseases (AITD) are the most prevalent organ-specific autoimmune
diseases (ADs) and affect 2-5% of the population (1) with great variability between genders …

[PDF][PDF] CTLA-4 gene polymorphisms and their influence on predisposition to autoimmune thyroid diseases (Graves' disease and Hashimoto's thyroiditis)

D Pastuszak-Lewandoska, E Sewerynek… - Archives of Medical …, 2012 - termedia.pl
Results: Statistical analysis (c2 test) confirmed significant differences between the studied
groups concerning CTLA-4 A49G genotypes. CTLA-4 A/G genotype was significantly more …

Genetic susceptibility to joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis: how far is our understanding?

N Zeber-Lubecka, EE Hennig - Frontiers in immunology, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) and Hashimoto's thyroiditis (HT) are endocrine disorders
that commonly occur among young women. A higher prevalence of HT in women with …

Interaction of HLA-DRB1* alleles and CTLA4 (+ 49 AG) gene polymorphism in autoimmune thyroid disease

S Ramgopal, C Rathika, MR Padma, V Murali, K Arun… - Gene, 2018 - Elsevier
Abstract Autoimmune Thyroid Diseases (AITDs), including Hashimoto's thyroiditis (HT) and
Graves' disease (GD), arise by the complex interaction of genes and environmental factors …

IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms

N Akeno, EP Smith, M Stefan, AK Huber… - The Journal of …, 2011 - journals.aai.org
IFN-α is known to play a key role in autoimmunity, but the mechanisms are uncertain.
Although the induction of autoimmunity by IFN-α is consistent with primarily …

Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes

Y Tomer, A Hasham, TF Davies, M Stefan… - The Journal of …, 2013 - academic.oup.com
Context: Genetic factors play a major role in the etiology of autoimmune thyroid disease
(AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). We have previously …