Peptide-based targeted therapeutics and apoptosis imaging probes for cancer therapy
Peptides have advantages over antibodies in terms of deep tissue penetration, low
immunogenicity, and cost-effective production, but they have short circulation time and poor …
immunogenicity, and cost-effective production, but they have short circulation time and poor …
HIV-associated cancer biomarkers: a requirement for early diagnosis
Globally, HIV/AIDS and cancer are increasingly public health problems and continue to exist
as comorbidities. The sub-Saharan African region has the largest number of HIV infections …
as comorbidities. The sub-Saharan African region has the largest number of HIV infections …
Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo
I Ramachandran, E Thavathiru, S Ramalingam… - Oncogene, 2012 - nature.com
Aberrant activation of Wingless-type (Wnt)/β-catenin signaling is widespread in human
cervical cancer. However, the underlying mechanisms of Wnt activation and the therapeutic …
cervical cancer. However, the underlying mechanisms of Wnt activation and the therapeutic …
Protein expression of CD44 (standard and variant isoforms) in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, p53 expression …
K Endo, T Terada - Journal of hepatology, 2000 - Elsevier
Background/Aims: Members of the CD44 family are transmembrane glycoproteins which act
mainly as receptors for hyaluronan. We have examined the expression of CD44s and …
mainly as receptors for hyaluronan. We have examined the expression of CD44s and …
Bladder Cancer Initiating Cells (BCICs) Are Among EMA−CD44v6+ Subset: Novel Methods for Isolating Undetermined Cancer Stem (Initiating) Cells
YM Yang, JW Chang - Cancer Investigation, 2008 - Taylor & Francis
Bladder cancer stem (initiating) cell has not been isolated now, and no one verified its
persistence experimentally. The aim of this study was to conclude the persistence of bladder …
persistence experimentally. The aim of this study was to conclude the persistence of bladder …
Reduced level of CD44 and hyaluronan associated with unfavorable prognosis in clinical stage I cutaneous melanoma
JM Karjalainen, RH Tammi, MI Tammi… - The American journal of …, 2000 - Elsevier
The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and
metastatic capacity of melanoma cells in vitro, but their clinical significance in primary …
metastatic capacity of melanoma cells in vitro, but their clinical significance in primary …
[PDF][PDF] Expression of E‐cadherin, α‐catenin, β‐catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study
K Ashida, T Terada, Y Kitamura, N Kaibara - Hepatology, 1998 - Wiley Online Library
Immunolocalization of E‐cadherin (E‐cad), α‐catenin, β‐catenin, and CD44 has rarely been
investigated in human cholangiocarcinoma (CC). We, therefore, immunohistochemically …
investigated in human cholangiocarcinoma (CC). We, therefore, immunohistochemically …
p38 kinase is crucial for osteopontin-induced furin expression that supports cervical cancer progression
Abstract p38 kinases activated by growth factors, hormones, and environmental stresses
exert diverse functions in regulating normal and malignant cell pathophysiology. Enhanced …
exert diverse functions in regulating normal and malignant cell pathophysiology. Enhanced …
The prognostic value of immunohistochemically detected CD44v3 and CD44v6 expression in patients with surgically staged vulvar carcinoma: a multicenter study
LA Hefler, N Concin, D Mincham, J Thompson… - Cancer, 2002 - Wiley Online Library
BACKGROUND Isoforms of the adhesion molecule CD44 are involved in carcinogenesis
and the metastatic cascade of tumor cells by increasing the affinity of malignant cells to their …
and the metastatic cascade of tumor cells by increasing the affinity of malignant cells to their …
Role of CD44 variant exon 6 in invasion of head and neck squamous cell carcinoma
M Kanke, M Fujii, K Kameyama, J Kanzaki… - … –Head & Neck …, 2000 - jamanetwork.com
Objectives To determine the correlation between the expression of CD44 variant exon 6 (v6)
and the clinicopathological features of head and neck squamous cell carcinomas …
and the clinicopathological features of head and neck squamous cell carcinomas …