Peptide-based targeted therapeutics and apoptosis imaging probes for cancer therapy

SMP Vadevoo, S Gurung, F Khan, ME Haque… - Archives of pharmacal …, 2019 - Springer
Peptides have advantages over antibodies in terms of deep tissue penetration, low
immunogenicity, and cost-effective production, but they have short circulation time and poor …

HIV-associated cancer biomarkers: a requirement for early diagnosis

Z Dlamini, M Mbele, TJ Makhafola, R Hull… - International Journal of …, 2021 - mdpi.com
Globally, HIV/AIDS and cancer are increasingly public health problems and continue to exist
as comorbidities. The sub-Saharan African region has the largest number of HIV infections …

Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo

I Ramachandran, E Thavathiru, S Ramalingam… - Oncogene, 2012 - nature.com
Aberrant activation of Wingless-type (Wnt)/β-catenin signaling is widespread in human
cervical cancer. However, the underlying mechanisms of Wnt activation and the therapeutic …

Protein expression of CD44 (standard and variant isoforms) in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, p53 expression …

K Endo, T Terada - Journal of hepatology, 2000 - Elsevier
Background/Aims: Members of the CD44 family are transmembrane glycoproteins which act
mainly as receptors for hyaluronan. We have examined the expression of CD44s and …

Bladder Cancer Initiating Cells (BCICs) Are Among EMACD44v6+ Subset: Novel Methods for Isolating Undetermined Cancer Stem (Initiating) Cells

YM Yang, JW Chang - Cancer Investigation, 2008 - Taylor & Francis
Bladder cancer stem (initiating) cell has not been isolated now, and no one verified its
persistence experimentally. The aim of this study was to conclude the persistence of bladder …

Reduced level of CD44 and hyaluronan associated with unfavorable prognosis in clinical stage I cutaneous melanoma

JM Karjalainen, RH Tammi, MI Tammi… - The American journal of …, 2000 - Elsevier
The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and
metastatic capacity of melanoma cells in vitro, but their clinical significance in primary …

[PDF][PDF] Expression of E‐cadherin, α‐catenin, β‐catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study

K Ashida, T Terada, Y Kitamura, N Kaibara - Hepatology, 1998 - Wiley Online Library
Immunolocalization of E‐cadherin (E‐cad), α‐catenin, β‐catenin, and CD44 has rarely been
investigated in human cholangiocarcinoma (CC). We, therefore, immunohistochemically …

p38 kinase is crucial for osteopontin-induced furin expression that supports cervical cancer progression

V Kumar, R Behera, K Lohite, S Karnik, GC Kundu - Cancer research, 2010 - AACR
Abstract p38 kinases activated by growth factors, hormones, and environmental stresses
exert diverse functions in regulating normal and malignant cell pathophysiology. Enhanced …

The prognostic value of immunohistochemically detected CD44v3 and CD44v6 expression in patients with surgically staged vulvar carcinoma: a multicenter study

LA Hefler, N Concin, D Mincham, J Thompson… - Cancer, 2002 - Wiley Online Library
BACKGROUND Isoforms of the adhesion molecule CD44 are involved in carcinogenesis
and the metastatic cascade of tumor cells by increasing the affinity of malignant cells to their …

Role of CD44 variant exon 6 in invasion of head and neck squamous cell carcinoma

M Kanke, M Fujii, K Kameyama, J Kanzaki… - … –Head & Neck …, 2000 - jamanetwork.com
Objectives To determine the correlation between the expression of CD44 variant exon 6 (v6)
and the clinicopathological features of head and neck squamous cell carcinomas …