Recent advances in nanostructure/nanomaterial-assisted laser desorption/ionization mass spectrometry of low molecular mass compounds

H He, Z Guo, Y Wen, S Xu, Z Liu - Analytica chimica acta, 2019 - Elsevier
Laser desorption ionization mass spectrometry (LDI-MS) has been developed to be an
essential tool for the analysis and identification of a large variety of species, ranging from …

Plasmonic silver nanoshells for drug and metabolite detection

L Huang, J Wan, X Wei, Y Liu, J Huang, X Sun… - Nature …, 2017 - nature.com
In-vitro metabolite and drug detection rely on designed materials-based analytical platforms,
which are universally used in biomedical research and clinical practice. However, metabolic …

Cysteine tagging for MS‐based proteomics

P Giron, L Dayon, JC Sanchez - Mass spectrometry reviews, 2011 - Wiley Online Library
Amino acid‐tagging strategies are widespread in proteomics. Because of the central role of
mass spectrometry (MS) as a detection technique in protein sciences, the term “mass …

Construction of a plasmonic chip for metabolic analysis in cervical cancer screening and evaluation

W Shu, Y Wang, C Liu, R Li, C Pei, W Lou, S Lin… - Small …, 2020 - Wiley Online Library
There is a high demand for high‐throughput in vitro metabolic analysis in clinical practice.
However, current metabolic analysis of biofluids requires tedious sample pretreatment due …

Effect of MALDI matrices on lipid analyses of biological tissues using MALDI‐2 postionization mass spectrometry

JC McMillen, JA Fincher, DR Klein… - Journal of mass …, 2020 - Wiley Online Library
Matrix‐assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows
for highly multiplexed, untargeted detection of many hundreds of analytes from tissue …

One-pot synthesis of dopamine dithiocarbamate functionalized gold nanoparticles for quantitative analysis of small molecules and phosphopeptides in SALDI-and …

SK Kailasa, HF Wu - Analyst, 2012 - pubs.rsc.org
The sensitivity and efficiency of SALDI-MS or MALDI-MS is mainly dependent on the nature
of matrix. A novel approach is proposed for one-pot synthesis of dopamine dithiocarbamate …

Detection of antimicrobial resistance-associated proteins by titanium dioxide-facilitated intact bacteria mass spectrometry

Y Zhu, N Gasilova, M Jović, L Qiao, B Liu, LT Lovey… - Chemical …, 2018 - pubs.rsc.org
Titanium dioxide-modified target plates were developed to enhance intact bacteria analysis
by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. The plates …

TiO2-Assisted Laser Desorption/Ionization Mass Spectrometry for Rapid Profiling of Candidate Metabolite Biomarkers from Antimicrobial-Resistant Bacteria

R Zhang, Q Qin, B Liu, L Qiao - Analytical chemistry, 2018 - ACS Publications
Antimicrobial resistance (AMR) is one of the most serious problems affecting public health
and safety. It is crucial to understand antimicrobial resistance from the molecular level. In this …

Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling

G Li, F Ma, Q Cao, Z Zheng, K DeLaney, R Liu… - Nature …, 2019 - nature.com
Comprehensive protein identification and concomitant structural probing of proteins are of
great biological significance. However, this is challenging to accomplish simultaneously in …

Analysis of major milk whey proteins by immunoaffinity capillary electrophoresis coupled with MALDI‐MS

N Gasilova, AL Gassner, HH Girault - Electrophoresis, 2012 - Wiley Online Library
Two major milk whey proteins, β‐lactoglobulin and α‐lactalbumin, are among the main cow
milk allergens and can cause allergy even at a very low concentrations. Therefore, these …