Glucose metabolism in cardiac hypertrophy and heart failure
Heart failure is one of the leading causes of death worldwide and has been singled out as
an emerging epidemic. 1, 2 With a 5-year survival rate of 50%, heart failure poses a …
an emerging epidemic. 1, 2 With a 5-year survival rate of 50%, heart failure poses a …
Myocardial fatty acid metabolism in health and disease
There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …
2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart …
PT O'Gara, FG Kushner, DD Ascheim, DE Casey… - Journal of the American …, 2013 - jacc.org
1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. The current document constitutes a full revision and …
whenever possible, evidence based. The current document constitutes a full revision and …
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion
LA Nikolaidis, S Mankad, GG Sokos, G Miske, A Shah… - Circulation, 2004 - Am Heart Assoc
Background—Glucose-insulin-potassium infusions are beneficial in uncomplicated patients
with acute myocardial infarction (AMI) but are of unproven efficacy in AMI with left ventricular …
with acute myocardial infarction (AMI) but are of unproven efficacy in AMI with left ventricular …
[HTML][HTML] Targeting fatty acid and carbohydrate oxidation—a novel therapeutic intervention in the ischemic and failing heart
Cardiac ischemia and its consequences including heart failure, which itself has emerged as
the leading cause of morbidity and mortality in developed countries are accompanied by …
the leading cause of morbidity and mortality in developed countries are accompanied by …
Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes
M Kosiborod, SS Rathore, SE Inzucchi, FA Masoudi… - Circulation, 2005 - Am Heart Assoc
Background—The relationship between admission glucose levels and outcomes in older
diabetic and nondiabetic patients with acute myocardial infarction is not well defined …
diabetic and nondiabetic patients with acute myocardial infarction is not well defined …
Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
GG Sokos, LA Nikolaidis, S Mankad, D Elahi… - Journal of cardiac …, 2006 - Elsevier
BACKGROUND: Insulin resistance is present in the setting of congestive heart failure.
Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and …
Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and …
[HTML][HTML] Hyperglycemia: a prothrombotic factor?
BA Lemkes, J Hermanides, JH DeVries… - Journal of Thrombosis …, 2010 - Elsevier
Diabetes mellitus is characterized by a high risk of atherothrombotic events. What is more,
venous thrombosis has also been found to occur more frequently in this patient group. This …
venous thrombosis has also been found to occur more frequently in this patient group. This …
Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury
L Timmers, JPS Henriques, DPV de Kleijn… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to examine whether exenatide is capable of reducing
myocardial infarct size. Background: Exenatide is a glucagon-like peptide (GLP)-1 analogue …
myocardial infarct size. Background: Exenatide is a glucagon-like peptide (GLP)-1 analogue …
Use of intensive insulin therapy for the management of glycemic control in hospitalized patients: a clinical practice guideline from the American College of Physicians
A Qaseem, LL Humphrey, R Chou, V Snow… - Annals of internal …, 2011 - acpjournals.org
Description: The American College of Physicians (ACP) developed this guideline to present
the evidence for the link between the use of intensive insulin therapy to achieve different …
the evidence for the link between the use of intensive insulin therapy to achieve different …