Domesticated plants and animals played crucial roles as models for evolutionary change by
means of natural selection and for establishing the rules of inheritance, originally proposed …

During the past few decades, advances in molecular genetics have led to the identification
of multiple genes or genetic markers associated with genes that affect traits of interest in …

One of the'grand challenges' in modern biology is to understand the genetic basis of
phenotypic diversity within and among species. Thousands of years of selective breeding of …

Farm animal populations harbour rich collections of mutations with phenotypic effects that
have been purposefully enriched by breeding. Most of these mutations do not have …

Agouti signaling protein (ASIP) functions to regulate pigmentation in mice, while its role in
many other animals and in humans has not been fully determined. In this study, we identify a …

Fig. 1 Test statistic curves obtained in QTL analyses of chromosome 2 in a Wild Boar/Large
White intercross. The graph plots the F ratio in a leastsquares analysis2, testing the …

The relative roles of the Kit receptor in promoting the migration and survival of amniote
melanocytes are unresolved. We show that, in the zebrafish, Danio rerio, the pigment pattern …

Vertebrate pigmentation patterns are amongst the best characterised model systems for
studying the genetic basis of adaptive evolution. The wealth of available data on the genetic …

Colour sidedness is a dominantly inherited phenotype of cattle characterized by the
polarization of pigmented sectors on the flanks, snout and ear tips. It is also referred to as …

Recent studies in humans and other model organisms have demonstrated that structural
variants (SVs) comprise a substantial proportion of variation among individuals of each …