The optimal choice of euthanasia method for laboratory rodents depends on a number of
factors, including the scientific goals of the study, the need to minimize animal pain and/or …

Rodents are the most widely used species for scientific purposes. A critical pre-requisite of
their use, based on utilitarian ethical reasoning, is the provision of a humane death when …

Rodents are widely used for animal research in Egypt. Pentobarbital is the most common
anesthetic agent; however overdoses may affect the experimental outcomes and limit the …

The impact of euthanasia methods on endocrine and metabolic parameters in rodent tissues
and biological fluids is highly relevant for the accuracy and reliability of the data collected …

Ulinastatin, a urinary trypsin inhibitor (UTI) is commonly used to treat patients with acute
inflammatory disease. However, the underlying mechanisms of its anti‑inflammatory effect in …

Several questions have been raised in recent years about the euthanasia of laboratory
rodents. Euthanasia using inhaled agents is considered to be a suitable aesthetic method …

Introduction: Endothelial dysfunction is a major risk factor for several of the vascular
complications of diabetes, including ischemic stroke. Nitroxyl (HNO), the one electron …

Laboratory animal professionals (LAP) are faced with various situations and tasks
influencing their mental well-being. A systematic review has been conducted to investigate …

Background Mast cells are known to affect the primary and secondary immune responses
against parasites, and this effect is partially mediated through the release of pro-angiogenic …

There is now substantial evidence that myocardial ischemia-reperfusion (IR) injury affects
the spinal cord and brain, and that interactions may exist between these two systems. In the …