Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …

Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

Global energy demand and environmental concerns have stimulated increasing efforts to
produce carbon-neutral fuels directly from renewable resources. Microbially derived …

Resveratrol is a naturally occurring stilbene endowed with multiple health-promoting effects.
It is produced by certain plants including several dietary sources such as grapes, apples …

In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …

Resveratrol is a plant secondary metabolite with multiple health-beneficial properties.
Microbial production of resveratrol in model microorganisms requires extensive engineering …

Plants have long been exploited as a sustainable source of food, flavors, agrochemicals,
colors, therapeutic proteins, bioactive compounds, and stem cell production. However, plant …

Metabolic engineering and synthetic biology have enabled the use of microbial production
platforms for the renewable production of many high-value natural products. Titers and …

Aromatic amino acids are precursors of numerous plant secondary metabolites with diverse
biological functions. Many of these secondary metabolites are already being used as active …