Thyroid cancer is the most common sort of endocrine-related cancer with more prevalent in
women and elderly individuals which has quickly widespread expansion in worldwide over …

Background: Metformin is one of the most widely prescribed antidiabetic medications with a
favorable safety profile. In the last decade, several studies have reported a TSH-lowering …

Different cancer cells exhibit altered sensitivity to metformin treatment. Recent studies
suggest these findings may be due in part to the common cell culture practice of utilizing …

Androgen receptor (AR)-mediated signaling is essential for the growth and differentiation of
the normal prostate and is the primary target for androgen deprivation therapy in prostate …

AMP-activated kinase (AMPK) is a serine/threonine kinase that is expressed in most cells
and activated by a high cellular AMP/ATP ratio (indicating energy deficiency) or by Ca2+. In …

Glucose represents an important source of energy for the cells. Proliferating cancer cells
consume elevated quantity of glucose, which is converted into lactate regardless of the …

Ketone bodies serve as an energy source, especially in the absence of carbohydrates or in
the extended exercise. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) …

In this study, we investigated the ability of curcumin alone or in combination with GLUT1
siRNA to radiosensitize laryngeal carcinoma (LC) through the induction of autophagy …

Background Use of metformin has been associated with a decreased cancer risk. We aimed
to explore whether use of metformin or other antidiabetic drugs is associated with a …

Abstract Purpose The AMPK-activator AICAR recently raised great interest for its anti-cancer
properties. With specific regard to thyroid cancer, AICAR reduces cancer cell growth …