Pyridine-based ring systems are one of the most extensively used heterocycles in the field of
drug design, primarily due to their profound effect on pharmacological activity, which has led …

Asymmetric catalysis has been recognized as the most enabling strategy for accessing
chiral molecules in enantioenriched forms. Catalytic asymmetric dearomatization is an …

Late-stage functionalization of C–H bonds (C–H LSF) can provide a straightforward
approach to the efficient synthesis of functionalized complex molecules. However, C–H LSF …

Photo-/electrochemical catalyzed oxidative R1-H/R2-H cross-coupling with hydrogen
evolution has become an increasingly important issue for molecular synthesis. The dream of …

The selective and efficient C–H methylation of sp2 and sp3 carbon centres has become a
powerful transformation in the synthetic toolbox. Due to the potential for profound changes to …

Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …

Reticular chemistry based on thermodynamically controlled linking modes and numerous
organic building blocks has constituted versatile crystalline frameworks in molecular-level …

Carbon-hydrogen (C− H) functionalization of pyridines is a powerful tool for the rapid
construction and derivatization of many agrochemicals, pharmaceuticals, and materials …

β-(Hetero) arylethylamines are privileged structural motifs found in many high-value organic
molecules, including pharmaceuticals and natural products. To construct these important …

Triazines are an important class of six-membered aromatic heterocycles possessing three
nitrogen atoms, resulting in three types of regio-isomers: 1, 2, 4-triazines (a-triazines), 1, 2, 3 …