Immune-related uncommon adverse events in patients with cancer treated with immunotherapy

V Albarrán-Artahona, JC Laguna, T Gorría… - Diagnostics, 2022 - mdpi.com
Immunotherapy has dramatically changed the therapeutic landscape of oncology, and has
become standard of care in multiple cancer types in front or late lines of therapy, with some …

Neurologic Complications of Cancer Immunotherapy

AN Alsalem, LA Scarffe, HR Briemberg, AE Aaroe… - Current …, 2023 - mdpi.com
Immunotherapy has revolutionized cancer treatment over the past decade. As it is
increasingly introduced into routine clinical practice, immune-related complications have …

A case report of neuromyelitis optica spectrum disorder induced by pembrolizumab treatment for lung adenocarcinoma: a clinical and immunohistochemical study

S Hirano, A Kojima, Y Nakayama, T Takeda… - BMC neurology, 2022 - Springer
Background We report a case of neuromyelitis optica spectrum disorders (NMOSD), who
developed after the pembrolizumab treatment, an immune checkpoint inhibitor, against lung …

Update on Neuro-ophthalmic Manifestations of Immune Checkpoint Inhibitors

A Chen, BK Chwalisz - Current Neurology and Neuroscience Reports, 2024 - Springer
Abstract Purpose of Review Immune checkpoint inhibitor (ICI) use has been on the rise for
treatment of many different malignancies. Subsequently, more has been learned about …

Neurologic manifestations of autoimmunity with immune checkpoint inhibitors

JA McCombe, E Sechi, A Zekeridou - Handbook of Clinical Neurology, 2024 - Elsevier
Immune checkpoint inhibitors (ICIs) are cancer immunotherapies that enhance the body's
own immune system to treat cancer. ICI treatment, however, can cause immune-related …

Evaluation and management of acute high-grade immunotherapy-related neurotoxicity

M Sandoval, AH Wechsler, Z Alhajji, J Viets-Upchurch… - Heliyon, 2023 - cell.com
Immune checkpoint inhibitor monoclonal antibodies allow the host's immune system to
attack tumors, which has revolutionized cancer care over the last decade. As the use of …

Anti‐aquaporin‐4 immunoglobulin G/anti‐myelin oligodendrocyte glycoprotein immunoglobulin G double‐positive paraneoplastic neurological syndrome in a patient …

A Siddiqui, D Ross, RH Jani, VC Prabhu… - Clinical and …, 2024 - Wiley Online Library
We report a rare case of paraneoplastic neurological syndrome with dual seropositivity of
anti‐aquaporin‐4 and myelin oligodendrocyte glycoprotein antibodies in a 40 year‐old …

Side effects, toxicity and ADRs of monoclonal antibodies in multiple organ systems

B Zhang, R Kumar, SD Ray - Side Effects of Drugs Annual, 2022 - Elsevier
The review of publications on the safety profiles of three different immunosuppressants and
immunomodulators (Alemtuzumab (ALZ), ipilimumab and nivolumab) published between …

Comparison of the PD-1 expression level in peripheral blood of Multiple Sclerosis and Neuromyelitis Optica patients

T Aghaie, M Gorgani, M Motallebnezhad… - Alborz University …, 2024 - aums.abzums.ac.ir
Programmed cell death-1 (PD-1) is one of the important co-inhibitory receptors in
maintaining tolerance and inhibiting the proliferation and activity of activated immune cells …