[HTML][HTML] Biophysics of lipid bilayers containing oxidatively modified phospholipids: insights from fluorescence and EPR experiments and from MD simulations

P Jurkiewicz, A Olżyńska, L Cwiklik, E Conte… - … et Biophysica Acta (BBA …, 2012 - Elsevier
This review focuses on the influence of oxidized phosphatidylcholines (oxPCs) on the
biophysical properties of model membranes and is limited to fluorescence, EPR, and MD …

Effects of nitro-oxidative stress on biomolecules: part 1—non-reactive molecular dynamics simulations

M Ghasemitarei, T Ghorbi, M Yusupov, Y Zhang… - Biomolecules, 2023 - mdpi.com
Plasma medicine, or the biomedical application of cold atmospheric plasma (CAP), is an
expanding field within plasma research. CAP has demonstrated remarkable versatility in …

Bilayer deformation, pores, and micellation induced by oxidized lipids

P Boonnoy, V Jarerattanachat… - The journal of …, 2015 - ACS Publications
The influence of different oxidized lipids on lipid bilayers was investigated with 16 individual
1 μs atomistic molecular dynamics (MD) simulations. Binary mixtures of lipid bilayers of 1 …

Cholesterol promotes the interaction of Alzheimer β-amyloid monomer with lipid bilayer

X Yu, J Zheng - Journal of molecular biology, 2012 - Elsevier
Cholesterol in the plasma membrane plays an important role in the pathogenesis of
Alzheimer's disease, but the exact function of cholesterol in the regulation of amyloid-β (Aβ) …

Organization of gangliosides into membrane nanodomains

MJ Sarmento, JC Ricardo, M Amaro, R Šachl - FEBS letters, 2020 - Wiley Online Library
Gangliosides are glycosphingolipids consisting of a ceramide base and a bulky sugar chain
that contains one or more sialic acids. This unique structure endows gangliosides with a …

Molecular-scale biophysical modulation of an endothelial membrane by oxidized phospholipids

MAA Ayee, E LeMaster, TP Shentu, DK Singh… - Biophysical journal, 2017 - cell.com
The influence of two bioactive oxidized phospholipids on model bilayer properties,
membrane packing, and endothelial cell biomechanics was investigated computationally …

Phase behavior and miscibility in lipid monolayers containing glycolipids

T Mukhina, G Brezesinski, C Shen… - Journal of Colloid and …, 2022 - Elsevier
Hypothesis Glycolipids in biological membranes are ubiquitous and believed to be involved
in the formation of ordered functional domains. However, our current knowledge about such …

Super-resolution stimulated emission depletion-fluorescence correlation spectroscopy reveals nanoscale membrane reorganization induced by pore-forming proteins

NK Sarangi, II P, KG Ayappa, SS Visweswariah… - Langmuir, 2016 - ACS Publications
Membrane–protein interactions play a central role in membrane mediated cellular
processes ranging from signaling, budding, and fusion, to transport across the cell …

Molecular dynamics study of oxidized lipid bilayers in NaCl solution

V Jarerattanachat, M Karttunen… - The Journal of Physical …, 2013 - ACS Publications
Polyunsaturated lipids are major targets of free radicals forming oxidized lipids through the
lipid peroxidation process. Thus, oxidized lipids play a significant role in cell membrane …

Pairing of cholesterol with oxidized phospholipid species in lipid bilayers

H Khandelia, B Loubet, A Olżyńska, P Jurkiewicz… - Soft Matter, 2014 - pubs.rsc.org
We claim that (1) cholesterol protects bilayers from disruption caused by lipid oxidation by
sequestering conical shaped oxidized lipid species such as 1-palmitoyl-2-azelaoyl-sn …