The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

mRNA vaccines: The dawn of a new era of cancer immunotherapy

Z Deng, Y Tian, J Song, G An, P Yang - Frontiers in Immunology, 2022 - frontiersin.org
mRNA therapy is a novel anticancer strategy based on in vitro transcription (IVT), which has
potential for the treatment of malignant tumors. The outbreak of the COVID-19 pandemic in …

Synthesis of green nanoparticles for energy, biomedical, environmental, agricultural, and food applications: A review

AI Osman, Y Zhang, M Farghali, AK Rashwan… - Environmental …, 2024 - Springer
Nanomaterials have been rapidly developed during the last decades, yet many
nanoparticles synthesized by classical methods are toxic and their synthesis procedure is …

Bioinspired Spatiotemporal Management toward RNA Therapies

Y Ma, S Li, X Lin, Y Chen - ACS nano, 2023 - ACS Publications
Ribonucleic acid (RNA)-based therapies have become an attractive topic in disease
intervention, especially with some that have been approved by the FDA such as the mRNA …

Advances in mRNA therapeutics for cancer immunotherapy: from modification to delivery

G Han, D Noh, H Lee, S Lee, S Kim, HY Yoon… - Advanced Drug Delivery …, 2023 - Elsevier
RNA vaccines have demonstrated their ability to solve the issues posed by the COVID-19
pandemic. This success has led to the renaissance of research into mRNA and their …

Folic acid conjugated poly (amidoamine) dendrimer as a smart nanocarriers for tracing, imaging, and treating cancers over-expressing folate receptors

M Fatima, A Sheikh, N Hasan, A Sahebkar… - European Polymer …, 2022 - Elsevier
Cancer is a deadly disease with complicated pathology. Present chemotherapy regimen
encounters challenges such as cytotoxicity, non-specificity and development of drug …

Gold nanoparticles: construction for drug delivery and application in cancer immunotherapy

H Huang, R Liu, J Yang, J Dai, S Fan, J Pi, Y Wei… - Pharmaceutics, 2023 - mdpi.com
Cancer immunotherapy is an innovative treatment strategy to enhance the ability of the
immune system to recognize and eliminate cancer cells. However, dose limitations, low …

Lipid nanoparticles: promising treatment approach for Parkinson's disease

K Jagaran, M Singh - International Journal of Molecular Sciences, 2022 - mdpi.com
Parkinson's disease (PD), a neurodegenerative disorder, is a life-altering, debilitating
disease exhibiting a severe physical, psychological, and financial burden on patients …

Nanomedicine for neurodegenerative disorders: Focus on Alzheimer's and Parkinson's diseases

K Jagaran, M Singh - International journal of molecular sciences, 2021 - mdpi.com
Neurodegenerative disorders involve the slow and gradual degeneration of axons and
neurons in the central nervous system (CNS), resulting in abnormalities in cellular function …