[HTML][HTML] Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity
Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …
membranes, and regulate energy metabolism. Questions remain as to which lipid species …
Peroxisomes: a nexus for lipid metabolism and cellular signaling
IJ Lodhi, CF Semenkovich - Cell metabolism, 2014 - cell.com
Peroxisomes are often dismissed as the cellular hoi polloi, relegated to cleaning up reactive
oxygen chemical debris discarded by other organelles. However, their functions extend far …
oxygen chemical debris discarded by other organelles. However, their functions extend far …
Metabolic interplay between peroxisomes and other subcellular organelles including mitochondria and the endoplasmic reticulum
RJA Wanders, HR Waterham… - Frontiers in cell and …, 2016 - frontiersin.org
Peroxisomes are unique subcellular organelles which play an indispensable role in several
key metabolic pathways which include:(1.) etherphospholipid biosynthesis;(2.) fatty acid …
key metabolic pathways which include:(1.) etherphospholipid biosynthesis;(2.) fatty acid …
The enzymes, regulation, and genetics of bile acid synthesis
DW Russell - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract The synthesis and excretion of bile acids comprise the major pathway of
cholesterol catabolism in mammals. Synthesis provides a direct means of converting …
cholesterol catabolism in mammals. Synthesis provides a direct means of converting …
[HTML][HTML] Interplay between oxidant species and energy metabolism
It has long been recognized that energy metabolism is linked to the production of reactive
oxygen species (ROS) and critical enzymes allied to metabolic pathways can be affected by …
oxygen species (ROS) and critical enzymes allied to metabolic pathways can be affected by …
Biochemistry of mammalian peroxisomes revisited
RJA Wanders, HR Waterham - Annu. Rev. Biochem., 2006 - annualreviews.org
In this review, we describe the current state of knowledge about the biochemistry of
mammalian peroxisomes, especially human peroxisomes. The identification and …
mammalian peroxisomes, especially human peroxisomes. The identification and …
PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR–ACTIVATED RECEPTOR α: An Adaptive Metabolic System
JK Reddy, T Hashimoto - Annual review of nutrition, 2001 - annualreviews.org
▪ Abstract β-Oxidation occurs in both mitochondria and peroxisomes. Mitochondria catalyze
the β-oxidation of the bulk of short-, medium-, and long-chain fatty acids derived from diet …
the β-oxidation of the bulk of short-, medium-, and long-chain fatty acids derived from diet …
Metabolic functions of peroxisomes in health and disease
RJA Wanders - Biochimie, 2014 - Elsevier
Peroxisomes are subcellular organelles which are present in virtually every eukaryotic cell
and catalyze a large number of metabolic functions. The importance of peroxisomes for …
and catalyze a large number of metabolic functions. The importance of peroxisomes for …
The biochemistry of peroxisomal β-oxidation in the yeast Saccharomyces cerevisiae
JK Hiltunen, AM Mursula… - FEMS microbiology …, 2003 - academic.oup.com
Peroxisomal fatty acid degradation in the yeast Saccharomyces cerevisiae requires an array
of β-oxidation enzyme activities as well as a set of auxiliary activities to provide the β …
of β-oxidation enzyme activities as well as a set of auxiliary activities to provide the β …
[HTML][HTML] Peroxisomal disorders: the single peroxisomal enzyme deficiencies
RJA Wanders, HR Waterham - … et Biophysica Acta (BBA)-Molecular Cell …, 2006 - Elsevier
Peroxisomal disorders are a group of inherited diseases in man in which either peroxisome
biogenesis or one or more peroxisomal functions are impaired. The peroxisomal disorders …
biogenesis or one or more peroxisomal functions are impaired. The peroxisomal disorders …