[HTML][HTML] Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity

H Yoon, JL Shaw, MC Haigis, A Greka - Molecular cell, 2021 - cell.com
Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …

Peroxisomes: a nexus for lipid metabolism and cellular signaling

IJ Lodhi, CF Semenkovich - Cell metabolism, 2014 - cell.com
Peroxisomes are often dismissed as the cellular hoi polloi, relegated to cleaning up reactive
oxygen chemical debris discarded by other organelles. However, their functions extend far …

Metabolic interplay between peroxisomes and other subcellular organelles including mitochondria and the endoplasmic reticulum

RJA Wanders, HR Waterham… - Frontiers in cell and …, 2016 - frontiersin.org
Peroxisomes are unique subcellular organelles which play an indispensable role in several
key metabolic pathways which include:(1.) etherphospholipid biosynthesis;(2.) fatty acid …

The enzymes, regulation, and genetics of bile acid synthesis

DW Russell - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract The synthesis and excretion of bile acids comprise the major pathway of
cholesterol catabolism in mammals. Synthesis provides a direct means of converting …

[HTML][HTML] Interplay between oxidant species and energy metabolism

C Quijano, M Trujillo, L Castro, A Trostchansky - Redox biology, 2016 - Elsevier
It has long been recognized that energy metabolism is linked to the production of reactive
oxygen species (ROS) and critical enzymes allied to metabolic pathways can be affected by …

Biochemistry of mammalian peroxisomes revisited

RJA Wanders, HR Waterham - Annu. Rev. Biochem., 2006 - annualreviews.org
In this review, we describe the current state of knowledge about the biochemistry of
mammalian peroxisomes, especially human peroxisomes. The identification and …

PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR–ACTIVATED RECEPTOR α: An Adaptive Metabolic System

JK Reddy, T Hashimoto - Annual review of nutrition, 2001 - annualreviews.org
▪ Abstract β-Oxidation occurs in both mitochondria and peroxisomes. Mitochondria catalyze
the β-oxidation of the bulk of short-, medium-, and long-chain fatty acids derived from diet …

Metabolic functions of peroxisomes in health and disease

RJA Wanders - Biochimie, 2014 - Elsevier
Peroxisomes are subcellular organelles which are present in virtually every eukaryotic cell
and catalyze a large number of metabolic functions. The importance of peroxisomes for …

The biochemistry of peroxisomal β-oxidation in the yeast Saccharomyces cerevisiae

JK Hiltunen, AM Mursula… - FEMS microbiology …, 2003 - academic.oup.com
Peroxisomal fatty acid degradation in the yeast Saccharomyces cerevisiae requires an array
of β-oxidation enzyme activities as well as a set of auxiliary activities to provide the β …

[HTML][HTML] Peroxisomal disorders: the single peroxisomal enzyme deficiencies

RJA Wanders, HR Waterham - … et Biophysica Acta (BBA)-Molecular Cell …, 2006 - Elsevier
Peroxisomal disorders are a group of inherited diseases in man in which either peroxisome
biogenesis or one or more peroxisomal functions are impaired. The peroxisomal disorders …