Proteomics by mass spectrometry: approaches, advances, and applications
Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale
proteomics. In this review, we dissect the overall framework of the MS experiment into its key …
proteomics. In this review, we dissect the overall framework of the MS experiment into its key …
Protein–protein interactions: switch from classical methods to proteomics and bioinformatics-based approaches
Following the sequencing of the human genome and many other organisms, research on
protein-coding genes and their functions (functional genomics) has intensified …
protein-coding genes and their functions (functional genomics) has intensified …
Metabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenance
LD Cohen, R Zuchman, O Sorokina, A Müller… - PloS one, 2013 - journals.plos.org
Chemical synapses contain multitudes of proteins, which in common with all proteins, have
finite lifetimes and therefore need to be continuously replaced. Given the huge numbers of …
finite lifetimes and therefore need to be continuously replaced. Given the huge numbers of …
Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes
OBJECTIVE Insulin resistance in skeletal muscle is an early phenomenon in the
pathogenesis of type 2 diabetes. Studies of insulin resistance usually are highly focused …
pathogenesis of type 2 diabetes. Studies of insulin resistance usually are highly focused …
Investigation of stable and transient protein–protein interactions: past, present, and future
This article presents an overview of the literature and a review of recent advances in the
analysis of stable and transient protein–protein interactions (PPI s) with a focus on their …
analysis of stable and transient protein–protein interactions (PPI s) with a focus on their …
Recent advances in quantitative neuroproteomics
GE Craft, A Chen, AC Nairn - Methods, 2013 - Elsevier
The field of proteomics is undergoing rapid development in a number of different areas
including improvements in mass spectrometric platforms, peptide identification algorithms …
including improvements in mass spectrometric platforms, peptide identification algorithms …
Quantitative proteomic analysis of primary neurons reveals diverse changes in synaptic protein content in fmr1 knockout mice
Fragile X syndrome (FXS) is a common inherited form of mental retardation that is caused, in
the vast majority of cases, by the transcriptional silencing of a single gene, fmr1. The …
the vast majority of cases, by the transcriptional silencing of a single gene, fmr1. The …
Direct comparison of MS‐based label‐free and SILAC quantitative proteome profiling strategies in primary retinal M üller cells
To better understand the involvement of retinal Müller glial (RMG) cells in retinal diseases,
we phenotyped primary porcine RMGs in dependence of cultivation time using different …
we phenotyped primary porcine RMGs in dependence of cultivation time using different …
Potential biomarkers in psychiatry: focus on the cholesterol system
AG Woods, I Sokolowska, R Taurines… - Journal of cellular …, 2012 - Wiley Online Library
Abstract● Introduction● Methods for proteomic analysis–Sample fractionation/biochemical
fractionation–MS● The cholesterol system–Cholesterol and apolipoproteins–Cholesterol …
fractionation–MS● The cholesterol system–Cholesterol and apolipoproteins–Cholesterol …
MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development
Summary Mammalian Sterile 20 (Ste20)-like kinase 3 (MST3) is a ubiquitously expressed
kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling …
kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling …