[HTML][HTML] Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

Eye tracking metrics to screen and assess cognitive impairment in patients with neurological disorders

L Tao, Q Wang, D Liu, J Wang, Z Zhu, L Feng - Neurological Sciences, 2020 - Springer
Purpose of review Eye tracking is a powerful method to investigate the relationship between
behavior and neural mechanisms. In recent years, eye movement analysis has been used in …

[HTML][HTML] Eye movement abnormalities in multiple sclerosis: pathogenesis, modeling, and treatment

A Serra, CG Chisari, M Matta - Frontiers in neurology, 2018 - frontiersin.org
Multiple sclerosis (MS) commonly causes eye movement abnormalities that may have a
significant impact on patients' disability. Inflammatory demyelinating lesions, especially …

[HTML][HTML] Oculomotor analysis to assess brain health: preliminary findings from a longitudinal study of multiple sclerosis using novel tablet-based eye-tracking software

É de Villers-Sidani, P Voss, N Bastien… - Frontiers in …, 2023 - frontiersin.org
A growing body of evidence supports the link between eye movement anomalies and brain
health. Indeed, the oculomotor system is composed of a diverse network of cortical and …

[HTML][HTML] Eye movement alterations in post-COVID-19 condition: A proof-of-concept study

C García Cena, MC Costa, R Saltarén Pazmiño… - Sensors, 2022 - mdpi.com
There is much evidence pointing out eye movement alterations in several neurological
diseases. To the best of our knowledge, this is the first video-oculography study describing …

[HTML][HTML] A standardized protocol for quantification of saccadic eye movements: DEMoNS

JA Nij Bijvank, A Petzold, LJ Balk, HS Tan… - PloS one, 2018 - journals.plos.org
Objective Quantitative saccadic testing is a non-invasive method of evaluating the neural
networks involved in the control of eye movements. The aim of this study is to provide a …

Visual deficits and cognitive assessment of multiple sclerosis: confounder, correlate, or both?

D Jakimovski, RHB Benedict, B Weinstock-Guttman… - Journal of …, 2021 - Springer
Background The relationship between visual impairment and cognitive performance in
multiple sclerosis (MS) remains poorly understood. Objective To determine associations …

Exogenous capture accounts for fundamental differences between pro-and antisaccade performance

AT Goldstein, TR Stanford, E Salinas - Elife, 2022 - elifesciences.org
To generate the next eye movement, oculomotor circuits take into consideration the physical
salience of objects in view and current behavioral goals, exogenous and endogenous …

Deconstructing the symbol digit modalities test in multiple sclerosis: The role of memory

VP Patel, LAS Walker, A Feinstein - Multiple sclerosis and related disorders, 2017 - Elsevier
Abstract Background The Symbol Digit Modalities Test (SDMT) is a sensitive measure of
impaired cognition in people with MS. While the SDMT is primarily considered a test of …

[HTML][HTML] Differential impact of sleep deprivation and circadian timing on reflexive versus inhibitory control of attention

J Collet, S Ftouni, M Clough, SW Cain, J Fielding… - Scientific Reports, 2020 - nature.com
In a visually stimulating environment with competing stimuli, we continually choose where to
allocate attention, and what to ignore. Wake and circadian-dependent modulation of …