Substitution of Coxsackievirus A16 VP1 BC and EF Loop Altered the Protective Immune Responses in Chimera Enterovirus A71
Hand, foot and mouth disease (HFMD) is a childhood disease caused by enterovirus A71
(EV-A71) and coxsackievirus A16 (CV-A16). Capsid loops are important epitopes for EV …
(EV-A71) and coxsackievirus A16 (CV-A16). Capsid loops are important epitopes for EV …
[HTML][HTML] Rational design of a DNA-launched live attenuated vaccine against human enterovirus 71
RR Zhang, MJ He, C Zhou, YP Xu, W Tang, TS Cao… - Virologica Sinica, 2024 - Elsevier
Abstract Human Enterovirus 71 (EV71) has emerged as one of the predominant causative
agents of hand, foot and mouth disease (HFMD) with global impact. Despite the inactivated …
agents of hand, foot and mouth disease (HFMD) with global impact. Despite the inactivated …
[HTML][HTML] Antiviral effects and mechanisms against EV71 of the novel 2-benzoxyl-phenylpyridine derivatives
A series of 2-Benzoxyl-Phenylpyridine derivatives were evaluated for their potential antiviral
activities against EV71. The preliminary assays indicated that some of these compounds …
activities against EV71. The preliminary assays indicated that some of these compounds …
Immunogenicity and protective efficacy of a multi-epitope recombinant toxin antigen of Pasteurella multocida against virulent challenge in mice
W Liang, H Xiao, JY Chen, YF Chang, SJ Cao, YP Wen… - Vaccine, 2023 - Elsevier
Pasteurella multocida (P. multocida) infection frequently results in porcine atrophic rhinitis
and swine plague, leading to large economic losses for the swine industry worldwide. P …
and swine plague, leading to large economic losses for the swine industry worldwide. P …
Modulation of plasmacytoid dendritic cell and CD4+ T cell differentiation accompanied by upregulation of the cholinergic anti-inflammatory pathway induced by …
L Li, RW Huang, XN Liu, XY Xiang, YT Zhou… - Archives of …, 2024 - Springer
Abstract Enterovirus 71 (EV71) is a neurotropic enterovirus associated with hand, foot, and
mouth disease (HFMD) fatalities. In this study, we investigated the impact of EV71 on …
mouth disease (HFMD) fatalities. In this study, we investigated the impact of EV71 on …
Structure-based virtual screening and fragment replacement to design novel inhibitors of Coxsackievirus A16 (CVA16)
J Zhou, Y Zhao, R Yang, Z Zhang, Y Jin… - Journal of …, 2023 - Taylor & Francis
Numerous studies have shown that hand, foot and mouth disease (HFMD) pathogen
Coxsackievirus A16 (CVA16) can also cause severe neurological complications and even …
Coxsackievirus A16 (CVA16) can also cause severe neurological complications and even …
Expression of polyprotein and 3D polymerase protein in Sf9 cells and immunogenicity against enterovirus A71B5 (Thailand strain)
N Issaro, A Kongkaew, A Jittmittraphap… - Journal of Applied …, 2023 - japsonline.com
Abstract Enterovirus 71 B5 subgenotype (EV-A71B5) is a primary human pathogen of hand,
foot, and mouth disease. In this study, we aimed to prepare a novel recombinant protein …
foot, and mouth disease. In this study, we aimed to prepare a novel recombinant protein …
抗人类肠道病毒71 药物及疫苗研究进展.
谢小晖， 陈路路， 李超英， 郑惠丹… - Journal of Modern …, 2023 - search.ebscohost.com
手足口病作为一个全球性的公共卫生问题, 危害巨大, 会引起患儿神经系统疾病, 具有高传染性,
传播方式多样, 病原体复杂多样等特点. 引起小儿手足口病的病原体主要为柯萨奇病毒A …
传播方式多样, 病原体复杂多样等特点. 引起小儿手足口病的病原体主要为柯萨奇病毒A …
直肠滴入中药对CoxA16, EV71 肠道病毒感染手足口病的疗效
毛梅， 陈波 - 中华养生保健, 2024 - zhysbjzz.com
目的观察直肠滴入中药对CoxA16, EV71 肠道病毒感染手足口病的疗效. 方法选取2019 年8 月—
2022 年8 月贵州水矿控股集团有限公司总医院CoxA16, EV71 肠道病毒感染手足口病患儿85 …
2022 年8 月贵州水矿控股集团有限公司总医院CoxA16, EV71 肠道病毒感染手足口病患儿85 …
Current therapeutic strategies and novel antiviral compounds for the treatment of nonpolio enteroviruses
AJ Suresh, RS Dass - Viral Infections and Antiviral Therapies, 2023 - Elsevier
The enteroviruses are simple, naked viruses capable of causing severe neurological,
respiratory, and systemic illnesses in immune-susceptible patients. Since the global …
respiratory, and systemic illnesses in immune-susceptible patients. Since the global …