As a gaseous second messenger, nitric oxide (NO) plays an important role in a series of
signal pathways. Research on the NO regulation for various disease treatments has aroused …

Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …

In order to precisely deliver celastrol into mitochondria of tumor cells, improve antitumor
efficacy of celastrol and overcome its troublesome problems in clinical application, a novel …

In this study, the porous cellulose microsphere carrier based on traditional Chinese
medicine waste was successfully used to prepare a molecularly imprinted polymer (SPCC …

Nowadays, among 3rd generation drug delivery systems, biodegradable polymeric based
long-acting injectable depot has achieved tremendous success in clinical application. So far …

Purpose Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer.
However, the effect of current treatment strategies by inducing tumor cell apoptosis alone is …

Objectives Previous studies elucidated that capecitabine (CAP) works as an anti-tumor
agent with putative immunosuppressive effects. However, the intricate mechanisms …

The incidence and mortality of cancer are gradually increasing. The highly invasive and
metastasis of tumor cells increase the difficulty of diagnosis and treatment, so people pay …

Celastrol (CSL), an active compound extracted from the root bark of Tripterygium wilfordii,
has been studied for its outstanding efficacy in anti-cancer and cerebral neurology. We have …

Background The growth, metastasis and treatment sensitivity of tumors can be strongly
influenced by Tumor-associated fibroblasts (TAFs) in the microenvironment. Effective cancer …