We describe a framework for defining pilot and feasibility studies focusing on studies
conducted in preparation for a randomised controlled trial. To develop the framework, we …

Feasibility studies are increasingly undertaken in preparation for randomised controlled
trials in order to explore uncertainties and enable trialists to optimise the intervention or the …

Background Implementation trials aim to test the effects of implementation strategies on the
adoption, integration or uptake of an evidence-based intervention within organisations or …

The Consolidated Standards of Reporting Trials (CONSORT) statement is a guideline
designed to improve the transparency and quality of the reporting of randomised controlled …

In this article, we highlight the distinctive features of a feasibility study, identify the main
objectives and guiding questions of a feasibility study, and illustrate the use of these …

Pilot studies play a vital role in health research, but are often misused, mistreated and
misrepresented. A well-conducted pilot study with clear aims and objectives within a formal …

Background A pilot study can be an important step in the assessment of an intervention by
providing information to design the future definitive trial. Pilot studies can be used to …

Many factors can affect the successful implementation and validity of intervention studies. A
primary purpose of feasibility and pilot studies is to assess the potential for successful …

Given increasing numbers of patients who are undergoing exome or genome sequencing, it
is critical to establish tools and methods to interpret the impact of genetic variation. While the …

Background Evaluations of complex interventions in public health are frequently
undermined by problems that can be identified before the effectiveness study stage …