Zebrafish models of sarcopenia

A Daya, R Donaka, D Karasik - Disease Models & …, 2020 - journals.biologists.com
Sarcopenia–the accelerated age-related loss of muscle mass and function–is an under-
diagnosed condition, and is central to deteriorating mobility, disability and frailty in older …

Modeling human muscular dystrophies in zebrafish: mutant lines, transgenic fluorescent biosensors, and phenotyping assays

C Tesoriero, F Greco, E Cannone, F Ghirotto… - International Journal of …, 2023 - mdpi.com
Muscular dystrophies (MDs) are a heterogeneous group of myopathies characterized by
progressive muscle weakness leading to death from heart or respiratory failure. MDs are …

In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish

Z Xiong, HP Lo, KA McMahon, N Martel, A Jones… - Elife, 2021 - elifesciences.org
Protein interaction networks are crucial for complex cellular processes. However, the
elucidation of protein interactions occurring within highly specialised cells and tissues is …

Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle

HP Lo, YW Lim, Z Xiong, N Martel, C Ferguson… - Journal of Cell …, 2021 - rupress.org
The cavin proteins are essential for caveola biogenesis and function. Here, we identify a role
for the muscle-specific component, Cavin4, in skeletal muscle T-tubule development by …

Model-based feedback control of live zebrafish behavior via interaction with a robotic replica

P De Lellis, E Cadolini, A Croce, Y Yang… - IEEE Transactions …, 2019 - ieeexplore.ieee.org
The possibility of regulating the behavior of live animals using biologically-inspired robots
has attracted the interest of biologists and engineers for over 25 years. From early work on …

NO-sGC Pathway Modulates Ca2+ Release and Muscle Contraction in Zebrafish Skeletal Muscle

Z Xiyuan, RHA Fink, M Mosqueira - Frontiers in Physiology, 2017 - frontiersin.org
Vertebrate skeletal muscle contraction and relaxation is a complex process that depends on
Ca2+ ions to promote the interaction of actin and myosin. This process can be modulated by …

Identification of potentially relevant genes for excessive exercise-induced pathological cardiac hypertrophy in zebrafish

Z Zhou, L Zheng, C Tang, Z Chen, R Zhu… - Frontiers in …, 2020 - frontiersin.org
Exercise-induced cardiac remodeling has aroused public concern for some time, as sudden
cardiac death is known to occur in athletes; however, little is known about the underlying …

Muscle-specific cavin4 interacts with bin1 to promote T-tubule formation and stability in developing skeletal muscle

HP Lo, YW Lim, Z Xiong, N Martel, C Ferguson… - bioRxiv, 2021 - biorxiv.org
The cavin proteins are essential for caveola biogenesis and function. Here, we identify a role
for the muscle-specific component, Cavin4, in skeletal muscle T-tubule development by …

Potential adaptive signaling pathways in the diaphragm of mdx mice treated with micro-dystrophin combined with voluntary running

LF McQueen - 2022 - vtechworks.lib.vt.edu
Hamm et al., 2021 reported that voluntary wheel running (R) was complementary to micro-
dystrophin gene therapy (GT) in mdx mice, a model of Duchenne muscular dystrophy …

Advances in the understanding of skeletal myopathies from zebrafish models

EC Baxter, RJ Bryson-Richardson - … Medaka, and Other Small Fishes: New …, 2018 - Springer
Skeletal muscle diseases, or myopathies, are a diverse group of disorders that range in
severity from mild muscle weakness to lethality and in onset from in utero to late adulthood …