Mucin-bacterial interactions in the human oral cavity and digestive tract

M Derrien, MWJ van Passel… - Gut …, 2010 - Taylor & Francis
Mucins are a family of heavily glycosylated proteins that are the major organic components
of the mucus layer, the protective layer covering the epithelial cells in many human and …

Saliva as research material: biochemical, physicochemical and practical aspects

RG Schipper, E Silletti, MH Vingerhoeds - Archives of oral biology, 2007 - Elsevier
Whole saliva is a complex mixture of proteins and other molecules which originate from
several sources. The biochemical and physicochemical properties of saliva contribute to the …

Saliva: a dynamic proteome

EJ Helmerhorst, FG Oppenheim - Journal of dental research, 2007 - journals.sagepub.com
The proteome of whole saliva, in contrast to that of serum, is highly susceptible to a variety of
physiological and biochemical processes. First, salivary protein secretion is under …

[HTML][HTML] Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7).

LA Bobek, H Tsai, AR Biesbrock, MJ Levine - Journal of Biological …, 1993 - Elsevier
Previous biochemical studies have determined that human saliva contains high and low
molecular weight mucin glycoproteins (MG1 and MG2, respectively) that are structurally …

[HTML][HTML] Salivary statherin. Dependence on sequence, charge, hydrogen bonding potency, and helical conformation for adsorption to hydroxyapatite and inhibition of …

PA Raj, M Johnsson, MJ Levine… - Journal of Biological …, 1992 - Elsevier
The structural domains of salivary statherin that are partly responsible for the protection and
recalcification of tooth enamel were examined with respect to charge, sequence …

Salivary proteome and its genetic polymorphisms

FG Oppenheim, E Salih, WL Siqueira… - Annals of the New …, 2007 - Wiley Online Library
Salivary diagnostics for oral as well as systemic diseases is dependent on the identification
of biomolecules reflecting a characteristic change in presence, absence, composition, or …

Human salivary mucin MG1 selectively forms heterotypic complexes with amylase, proline-rich proteins, statherin, and histatins

I Iontcheva, FG Oppenheim… - Journal of dental …, 1997 - journals.sagepub.com
Heterotypic complexes between the high-molecular-weight mucin MG1 and other salivary
proteins in human submandibular/sublingual secretion (HSMSL) could have a significant …

Quinoline-based photolabile protection strategy facilitates efficient protein assembly

S Wang, Q Zhou, Y Li, B Wei, X Liu, J Zhao… - Journal of the …, 2022 - ACS Publications
Native chemical ligation (NCL) provides a powerful solution to assemble proteins with
precise chemical features, which enables a detailed investigation of the protein structure …

Interaction of a salivary mucin-secretory immunoglobulin A complex with mucosal pathogens

AR Biesbrock, MS Reddy, MJ Levine - Infection and immunity, 1991 - Am Soc Microbiol
This study examined the interaction of a human salivary low-molecular-weight mucin (MG2)
with Staphylococcus aureus and Pseudomonas aeruginosa by using both solution-phase …

Cystatins—inhibitors of cysteine proteinases

LA Bobek, MJ Levine - Critical Reviews in Oral Biology & …, 1992 - journals.sagepub.com
The cystatin superfamily of proteins, derived from a common ancestor, is comprised of a
diverse group of potent cysteine proteinase inhibitors and antibacterial/viral agents grouped …