Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin
formation and gene silencing. It has a fundamental role in preserving genome stability …

Mobile elements and repetitive genomic regions are sources of lineage-specific genomic
innovation and uniquely fingerprint individual genomes. Comprehensive analyses of such …

Long noncoding RNAs (lncRNAs) are extremely diverse and have various significant
physiological functions. lncRNAs generally associate with specific sets of RNA‐binding …

Paraspeckles are constructed by NEAT1_2 architectural long noncoding RNAs. Their
characteristic cylindrical shapes, with highly ordered internal organization, distinguish them …

Biomolecules specifically aggregate in the cytoplasm and nucleus, driving liquid-liquid
phase separation (LLPS) formation and diverse biological processes. Extensive studies …

RNAs and RNA-binding proteins can undergo spontaneous or active condensation into
phase-separated liquid-like droplets. These condensates are cellular hubs for various …

Most of the human genome, except for a small region that transcribes protein-coding RNAs,
was considered junk. With the advent of RNA sequencing technology, we know that much of …

Post-transcriptional modifications to coding and non-coding RNAs are unquestionably a
pivotal way in which human mRNA and protein diversity can influence the different phases …

Long noncoding RNAs (lncRNAs) are fundamental regulators of various cellular processes.
A subset of lncRNAs, termed architectural RNAs (arcRNAs), function in the formation and …

Colorectal carcinogenesis is a multistep process involving the accumulation of genetic
alterations over time that ultimately leads to disease progression and metastasis. Binding of …