Various immune mechanisms are deployed in the mucosa to confront the immense diversity
of resident bacteria. A substantial fraction of the commensal microbiota is coated with …

The diagnosis, investigation and particularly management of bronchiectasis has been
largely empirical and the subject of relatively few controlled clinical trials. There are no clear …

Gastrointestinal microbiota and immune cells interact closely and display regional
specificity; however, little is known about how these communities differ with location. Here …

Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of
the intestinal microbiota. However, the commensal bacteria bound by IgA are poorly …

The growing world population (7.8 billion) exerts an increased pressure on the cattle
industry amongst others. Intensification and expansion of milk and beef production inevitably …

Abstract Introduction Immunoglobulin A (IgA) deficiency is the most common primary
immunodeficiency defined as decreased serum level of IgA in the presence of normal levels …

Selective immunoglobulin A deficiency (SI g AD) is the most common primary antibody
deficiency. Although more patients with SI g AD are asymptomatic, selected patients suffer …

The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

The tumor necrosis factor receptor family member TACI (transmembrane activator and
calcium-modulator and cyclophilin ligand interactor) mediates isotype switching in B cells …

The purpose of this Practice Parameter for the Diagnosis and Management of Primary
Immunodeficiency is to provide the consultant allergist/immunologist with a practical guide …