3-(((1S,3S)-3-((R)-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target …

A Sadiq, MH Mahnashi, U Rashid, MS Jan… - Molecules, 2022 - mdpi.com
The chiral drug candidates have more effective binding affinities for their specific protein or
receptor site for the onset of pharmacological action. Achieving all carbon stereopure …

A general and mild synthetic method for fused-ring electronic acceptors

X Zhong, S Liu, W You - Science Advances, 2024 - science.org
Fused-ring electronic acceptors (FREAs) have transformed the field of organic solar cells.
However, the prevailing syntheses of FREAs suffer from low yield, difficulty in separation …

A 2000 to 2020 Practitioner's Guide to Chiral Amine‐Based Enantioselective Aldol Reactions: Ketone Substrates, Best Methods, in Water Reaction Environments, and …

TC Nugent, AE de Vos, I Hussain… - European Journal of …, 2022 - Wiley Online Library
An extensive introduction is provided for the non‐expert regarding enantioselective, amine
catalyzed, aldol reactions (Sections 1–3). There, a broad perspective is provided regarding …

Enantioselective Catalytic Aldol Reactions in the Presence of Knoevenagel Nucleophiles: A Chemoselective Switch Optimized in Deep Eutectic Solvents Using …

H Al Beiruty, SS Zhylinska, N Kutateladze… - Molecules, 2023 - mdpi.com
In the presence of different nucleophilic Knoevenagel competitors, cyclic and acyclic
ketones have been shown to undergo highly chemoselective aldol reactions with aldehydes …

[引用][C] A 2000 to 2020 Practitioner's Guide to Chiral Amine Based Enantioselective Aldol Reactions: Common Ketone Substrates, Best Methods, in Water Reaction …