The presence of particles is a major issue during therapeutic protein formulation
development. Both proteinaceous and nonproteinaceous particles need to be analyzed not …

Pegfilgrastim is a sustained-duration form of filgrastim, a recombinant methionyl form of
human granulocyte colony-stimulating factor (G-CSF), to which a 20 kDa polyethylene glycol …

Nanofibers (NFs) provide several delivery advantages like their great flexibility and similarity
with extracellular matrix (ECM) which qualify them to be the unique model of a wound …

The interaction of magnetic iron oxide nanoparticles (MNPs) with bovine serum albumin
(BSA) was investigated by fluorescence (FL), ultraviolet visible (UV− vis) absorption, Raman …

Wafers combining weight ratios of Polyox with carrageenan (75/25) or sodium alginate
(50/50) containing streptomycin and diclofenac were prepared to improve chronic wound …

Chemical stability is a major concern in the development of protein therapeutics due to its
impact on both efficacy and safety. Protein “hotspots” are amino acid residues that are …

Therapeutic proteins as biopharmaceuticals have emerged as a very important class of
drugs for the treatment of many diseases. However, they are less stable compared to …

Based on the latest scientific knowledge about the antioxidant stress being the main trigger
factor for the development of Alzheimer's disease (AD) and the advantages of …

Nanoparticles (NPs) are extensively being used in modern nano-based therapies and nano-
protein formulations. The exposures to these comprehensively used NPs lead to changes in …

Immunoengineering technologies harness the power of immune system modulators such as
monoclonal antibodies, cytokines, and vaccines to treat myriad diseases …