The tetratricopeptide repeat (TPR) motif is a protein‐protein interaction module found in
multiple copies in a number of functionally different proteins that facilitates specific …

Defects in PEX genes impair peroxisome assembly and multiple metabolic pathways
confined to this organelle, thus providing the biochemical and molecular bases of the …

Peroxisomes are ubiquitous organelles whose dysfunction causes fatal human diseases.
Most peroxisomal enzymes are imported from the cytosol by the receptor PEX5, which …

Exosomes are small extracellular vesicles of∼ 30 to 150 nm that are secreted by all cells,
abundant in all biofluids, and play important roles in health and disease. However, details …

Peroxisome Function, Biogenesis, and Dynamics in Plants | Plant Physiology | Oxford
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Translocation of proteins across membranes of the endoplasmic reticulum, mitochondrion,
and chloroplast has been shown to be mediated by targeting signals present in the …

Peroxisomes contain numerous enzymatic activities that are important for mammalian
physiology. Patients lacking either all peroxisomal functions or a single enzyme or …

Rhizomelic chondrodysplasia punctata (RCDP) is a rare autosomal recessive phenotype
that comprises complementation group 11 of the peroxisome biogenesis disorders (PBD) …

Sensing viruses by pattern recognition receptors (PRR) triggers the innate immune system
of the host cell and activates immune signaling cascades such as the RIG-I/IRF3 pathway …

Oligodendrocytes myelinate axons for rapid impulse conduction and contribute to normal
axonal functions in the central nervous system. In multiple sclerosis, demyelination is …