Bacterial conjugation is an efficient and sophisticated mechanism of DNA transfer among
bacteria. While mobilizable plasmids only encode a minimal MOB machinery that allows …

Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

Conjugative relaxases are well-characterized proteins responsible for the site-and strand-
specific endonucleolytic cleavage and strand transfer reactions taking place at the start and …

Host-targeting type IV secretion systems (T4SS) evolved from conjugative T4SS machineries
that mediate interbacterial plasmid transfer. However, the origins of effectors secreted by …

Staphylococcus aureus is a common cause of hospital, community and livestock-associated
infections and is increasingly resistant to multiple antimicrobials. A significant proportion of …

The connectivity of a gene, defined as the number of interactions a gene's product has with
other genes' products, is a key characteristic of a gene. In prokaryotes, the complexity …

Plasmids are key vehicles of horizontal gene transfer and contribute greatly to bacterial
genome plasticity. In this work, we studied a group of plasmids from enterobacteria that …

Conjugative transfer from Clostridium symbiosum to enterococci of Tn 1549, which confers
VanB-type vancomycin resistance, has been reported. This indicates the presence of a …

Sinorhizobium meliloti 1021 carries two megaplasmids, pSymA of 1,354 kb and pSymB of
1,683 kb, which are essential in establishing symbiosis with its legume hosts and important …

Plasmid pAD1 is a 60-kb conjugative element commonly found in clinical isolates of
Enterococcus faecalis. The relaxase TraX and the primary origin of transfer oriT2 are located …