Microbiota-orientated treatments for major depression and schizophrenia

GB Fond, JC Lagier, S Honore, C Lancon, T Korchia… - Nutrients, 2020 - mdpi.com
Background and significance. There is a need to develop new hypothesis-driven treatment
for both both major depression (MD) and schizophrenia in which the risk of depression is 5 …

C-reactive protein as a peripheral biomarker in schizophrenia. An updated systematic review

G Fond, C Lançon, P Auquier, L Boyer - Frontiers in psychiatry, 2018 - frontiersin.org
Objectives: The objective of this systematic review was to synthetize the published data on
the relationships between elevated blood C-reactive protein (CRP) levels and schizophrenia …

Is it time for immunopsychiatry in psychotic disorders?

M Leboyer, J Oliveira, R Tamouza, L Groc - Psychopharmacology, 2016 - Springer
Introduction: Immune dysregulation is suggested to play an important aetiological role in
schizophrenia (SZ) and bipolar disorder (BD) potentially driving neurodevelopmental …

Chronic peripheral inflammation is associated with cognitive impairment in schizophrenia: results from the multicentric FACE-SZ dataset

E Bulzacka, L Boyer, F Schürhoff, O Godin… - Schizophrenia …, 2016 - academic.oup.com
Objectives: Inflammation, measured by abnormal blood C-reactive protein (CRP) level, has
been described in schizophrenia (SZ), being inconsistently related to impaired cognitive …

Uric acid levels in subjects with bipolar disorder: a comparative meta-analysis

F Bartoli, C Crocamo, MG Mazza, M Clerici… - Journal of Psychiatric …, 2016 - Elsevier
Previous research has hypothesised increased uric acid levels, possibly because of an
amplified purinergic metabolism and a reduced adenosine activity, in subjects with bipolar …

Visceral adipose accumulation increased the risk of hyperuricemia among middle-aged and elderly adults: a population-based study

X Huang, X Jiang, L Wang, L Chen, Y Wu… - Journal of Translational …, 2019 - Springer
Background The role of body fat distribution in uric acid metabolism is still ambiguity. We
aimed to investigate the independent contribution of visceral adipose measured by visceral …

Sexual dysfunctions in schizophrenia: Beyond antipsychotics. A systematic review

M Dumontaud, T Korchia, J Khouani, C Lançon… - Progress in Neuro …, 2020 - Elsevier
Background Sexual dysfunctions (SD) in schizophrenia are frequent with strong impact on
adherence and quality of life. Current recommendations stipulate to switch to prolactin …

Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade

L Rødevand, NE Steen, T Elvsåshagen… - Acta Psychiatrica …, 2019 - Wiley Online Library
Objective While CVD risk has decreased in the general population during the last decade,
the situation in patients with schizophrenia (SCZ) and bipolar disorder (BD) is unknown …

Remission of depression in patients with schizophrenia and comorbid major depressive disorder: results from the FACE-SZ cohort

G Fond, L Boyer, F Berna, O Godin… - The British Journal of …, 2018 - cambridge.org
BackgroundMajor depressive disorder (MDD) is underdiagnosed and undertreated in
schizophrenia, and has been strongly associated with impaired quality of life. AimsTo …

Metabolic and psychiatric effects of acyl coenzyme A binding protein (ACBP)/diazepam binding inhibitor (DBI)

A Joseph, S Moriceau, V Sica… - Cell Death & …, 2020 - nature.com
Acyl coenzyme A binding protein (ACBP), also known as diazepam binding inhibitor (DBI) is
a multifunctional protein with an intracellular action (as ACBP), as well as with an …