Clozapine and long-term mortality risk in patients with schizophrenia: a systematic review and meta-analysis of studies lasting 1.1–12.5 years
JM Vermeulen, G van Rooijen… - Schizophrenia …, 2019 - academic.oup.com
Introduction Patients with schizophrenia have an elevated mortality risk compared to the
general population, with cardiovascular-related deaths being the leading cause. The role of …
general population, with cardiovascular-related deaths being the leading cause. The role of …
Pathophysiological mechanisms of increased cardiometabolic risk in people with schizophrenia and other severe mental illnesses
DC Henderson, B Vincenzi, NV Andrea… - The Lancet …, 2015 - thelancet.com
Patients with schizophrenia have increased mortality and morbidity compared with the
general population. These patients have a 20-year shorter lifespan than peers without …
general population. These patients have a 20-year shorter lifespan than peers without …
Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic …
JP McEvoy, JA Lieberman, TS Stroup… - American Journal of …, 2006 - Am Psychiatric Assoc
Objective: When a schizophrenia patient has an inadequate response to treatment with an
antipsychotic drug, it is unclear what other antipsychotic to switch to and when to use …
antipsychotic drug, it is unclear what other antipsychotic to switch to and when to use …
[HTML][HTML] Clozapine as a model for antipsychotic development
FC Nucifora Jr, M Mihaljevic, BJ Lee, A Sawa - Neurotherapeutics, 2017 - Elsevier
Schizophrenia is a devastating illness that affects up to 1% of the population; it is
characterized by a combination of positive symptoms, negative symptoms, and cognitive …
characterized by a combination of positive symptoms, negative symptoms, and cognitive …
[图书][B] The Maudsley prescribing guidelines
D Taylor, C Paton - 2009 - taylorfrancis.com
One of the most widely used guides to prescribing psychiatric medications, the Tenth Edition
of Maudsley Prescribing Guidelines returns with fully updated content and new sections on …
of Maudsley Prescribing Guidelines returns with fully updated content and new sections on …
Termination of clozapine treatment due to medical reasons: when is it warranted and how can it be avoided
J Nielsen, CU Correll, P Manu, JM Kane - J Clin Psychiatry, 2013 - psychiatrist.com
Objective: To identify the outcome of potentially serious adverse effects of clozapine,
particularly those frequently cited as reasons for clozapine discontinuation, and to …
particularly those frequently cited as reasons for clozapine discontinuation, and to …
Atypical antipsychotics dose dependent? A literature review
V Simon, R Van Winkel, M De Hert - J Clin Psych, 2009 - psychiatrist.com
Background: Numerous publications have provided evidence for clinically important
metabolic adverse effects of antipsychotics, but there is no systematic evaluation as to …
metabolic adverse effects of antipsychotics, but there is no systematic evaluation as to …
Change in metabolic syndrome parameters with antipsychotic treatment in the CATIE Schizophrenia Trial: prospective data from phase 1
JM Meyer, VG Davis, DC Goff, JP McEvoy… - Schizophrenia …, 2008 - Elsevier
BACKGROUND: The metabolic syndrome (MS) is associated with increased risk for
diabetes mellitus and coronary heart disease, and is highly prevalent among schizophrenia …
diabetes mellitus and coronary heart disease, and is highly prevalent among schizophrenia …
Influence of antipsychotics on mortality in schizophrenia: systematic review
S Weinmann, J Read, V Aderhold - Schizophrenia research, 2009 - Elsevier
BACKGROUND: Antipsychotic medication is the cornerstone of schizophrenia treatment.
The impact of long-term exposure to antipsychotics on life-expectancy has recently received …
The impact of long-term exposure to antipsychotics on life-expectancy has recently received …
Interventions to reduce weight gain in schizophrenia
G Faulkner, T Cohn… - Cochrane Database of …, 2007 - cochranelibrary.com
Background Weight gain is common for people with schizophrenia and this has serious
implications for health and well being. Objectives To determine the effects of both …
implications for health and well being. Objectives To determine the effects of both …