The fission yeast Schizosaccharomyces pombe is an important model organism for the study
of eukaryotic molecular and cellular biology. Studies of S. pombe, together with studies of its …

Sister chromatids are held together by a protein complex named cohesin. Shugoshin
proteins protect cohesin from cleavage by separase during meiosis I in eukaryotes and from …

Genomic instability is a characteristic of most cancer cells. It is an increased tendency of
genome alteration during cell division. Cancer frequently results from damage to multiple …

The identification of cancer biomarkers is critical for target‐linked cancer therapy. The
overall level of phosphatidylcholine (PC) is elevated in colorectal cancer (CRC). To …

The genome-wide clustered regularly interspaced short palindromic repeats (CRISPR)
screen is a powerful tool used to identify therapeutic targets that can be harnessed for …

Triclocarban (TCC) is a widely used antibacterial ingredient possessing acute toxicity
effects; however, its chronic toxicity and underlying molecular mechanisms remain …

Accumulating evidence indicates that cancer cells show specific alterations in phospholipid
metabolism that contribute to tumour progression in several types of cancer, including …

Abstract Shugoshin-like protein 1 (Sgo1) is an essential protein in mitosis; it protects sister
chromatid cohesion and thereby ensures the fidelity of chromosome separation. We found …

Maximum number of drinks (MaxDrinks) defined as “Maximum number of alcoholic drinks
consumed in a 24-h period” is an intermediate phenotype that is closely related to alcohol …

Proper bioriented attachment of microtubules and kinetochores is essential for the precise
distribution of duplicated chromosomes to each daughter cell. An aberrant kinetochore …