Naringin and Hesperidin Counteract Diclofenac‐Induced Hepatotoxicity in Male Wistar Rats via Their Antioxidant, Anti‐Inflammatory, and Antiapoptotic Activities

RA Hassan, WG Hozayen, HT Abo Sree… - Oxidative medicine …, 2021 - Wiley Online Library
This study is aimed at evaluating the preventive effect and at suggesting the mode of actions
of naringin and hesperidin and their combination in diclofenac‐induced hepatotoxicity. Male …

Curcumin ameliorates diclofenac sodium‐induced nephrotoxicity in male albino rats

AY Ahmed, AM Gad… - Journal of biochemical …, 2017 - Wiley Online Library
Exposure to drugs often results in toxicity in the kidney which represents the major control
system maintaining homeostasis of the body and thus is especially susceptible to …

As a painkiller: a review of pre-and postnatal non-steroidal anti-inflammatory drug exposure effects on the nervous systems

KK Yurt, S Kaplan - Inflammopharmacology, 2018 - Springer
Diclofenac sodium (DS) is commonly used for the treatment of acute and chronic pain, even
for extended periods of time. Over the years, DS has been associated with toxicity in nervous …

Pharmacological effects of vitamin C & E on diclofenac sodium intoxicated rats

RA El-Shafei, RM Saleh - Biomedicine & pharmacotherapy, 2016 - Elsevier
Objective The aim of this study was to evaluate the probable protective effect of vitamin C
and vitamin E on diclofenac-induced acute nephrotoxicity using biochemical, molecular and …

The effect of tyrosol on diclofenac sodium‐induced acute nephrotoxicity in rats

M Çömez, M Cellat, M Kuzu, A Uyar… - … of Biochemical and …, 2024 - Wiley Online Library
Although diclofenac (DCF) is a nonsteroidal anti‐inflammatory drug that is considered safe,
its chronic use and overdose may show some toxic effects. The protective effect of tyrosol …

Protective effect of L-carnitine on experimental lead toxicity in rats: a clinical, histopathological and immunohistochemical study

SY Ozsoy, B Ozsoy, Z Ozyildiz… - Biotechnic & …, 2011 - Taylor & Francis
Female Wistar-albino rats were given lead acetate (PbAc) for 60 days to investigate the
protective effects of L-carnitine (CA) clinically and histopathologically on PbAc-induced …

[HTML][HTML] Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats

AC Famurewa, GG Akunna, J Nwafor… - Avicenna Journal of …, 2020 - ncbi.nlm.nih.gov
Objective: Diclofenac is a non-steroidal anti-inflammatory drug linked with considerable
organ toxicity caused via increased generation of reactive oxygen species. We evaluated …

Hematological and renoprotective effects of folic acid and lentil extract in diclofenac sodium exposed rats

ON Abdel-Rahman, ES Abdel-Baky - Brazilian Journal of Biology, 2021 - SciELO Brasil
Excessive intake of non-steroidal anti-inflammatory drugs such as, diclofenac sodium (DS)
may lead to toxicity in the rats. In this work, we aimed to examine the protective impact of …

The aqueous extract of Olea europaea leaves protects from haematotoxicity and kidney damage induced by diclofenac in Swiss albino mice

R Soussi, N Hfaiedh, M Sakly, KB Rhouma - RSC advances, 2019 - pubs.rsc.org
Olea europaea leaves are one of the most widely used by-products in traditional medicine
due to their biological properties. This study evaluated the antioxidant activities, and the …

[PDF][PDF] Stereological and biochemical evaluation of diclofenac-induced acute nephrotoxicity in rats

D Bolat, ML Selcuk - Revue Med Vet, 2013 - researchgate.net
The aim of this study was to evaluate the effects of diclofenac-induced acute nephrotoxicity
using stereological and biochemical parameters in rats. For that, 20 male Wistar rats allotted …