Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries

H Levine, N Jørgensen… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Numerous studies have reported declines in semen quality and other
markers of male reproductive health. Our previous meta-analysis reported a significant …

[HTML][HTML] Telomere dysfunction in ageing and age-related diseases

F Rossiello, D Jurk, JF Passos… - Nature cell …, 2022 - nature.com
Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

Temporal trends in sperm count: a systematic review and meta-regression analysis

H Levine, N Jørgensen… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Reported declines in sperm counts remain controversial today and recent
trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm …

Oxidative stress and male infertility

S Bisht, M Faiq, M Tolahunase, R Dada - Nature Reviews Urology, 2017 - nature.com
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Role of reactive oxygen species in aging and age-related diseases: a review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

[HTML][HTML] Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring

R Sharma, A Agarwal, VK Rohra, M Assidi… - Reproductive Biology …, 2015 - Springer
Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …

[HTML][HTML] Oxidative stress and male reproductive health

RJ Aitken, TB Smith, MS Jobling, MA Baker… - Asian journal of …, 2014 - journals.lww.com
One of the major causes of defective sperm function is oxidative stress, which not only
disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a …

[HTML][HTML] Impact of advanced paternal age on fertility and risks of genetic disorders in offspring

A Kaltsas, E Moustakli, A Zikopoulos, I Georgiou… - Genes, 2023 - mdpi.com
The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …

Impact of yoga and meditation on cellular aging in apparently healthy individuals: A prospective, open‐label single‐arm exploratory study

M Tolahunase, R Sagar, R Dada - Oxidative medicine and …, 2017 - Wiley Online Library
This study was designed to explore the impact of Yoga and Meditation based lifestyle
intervention (YMLI) on cellular aging in apparently healthy individuals. During this 12‐week …

Advances in sperm analysis: techniques, discoveries and applications

C Dai, Z Zhang, G Shan, LT Chu, Z Huang… - Nature Reviews …, 2021 - nature.com
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …